STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACR17740.1Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (170 aa)    
Predicted Functional Partners:
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
  
 0.988
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
 
 
 0.974
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.965
hpt
Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
 0.956
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
 0.929
ACR17776.1
GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.924
ACR16909.1
Putative pyruvate kinase-like protein.
  
 
 0.912
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.912
ACR17696.1
Hypothetical protein; GMP synthase - Glutamine amidotransferase domain.
  
 
 0.912
ACR18135.1
Hypothetical protein; GMP synthase - Glutamine amidotransferase domain.
  
 
 0.912
Your Current Organism:
Corynebacterium kroppenstedtii
NCBI taxonomy Id: 645127
Other names: C. kroppenstedtii DSM 44385, Corynebacterium kroppenstedtii CCUG 35717, Corynebacterium kroppenstedtii CIP 105744, Corynebacterium kroppenstedtii DSM 44385, Corynebacterium kroppenstedtii str. DSM 44385, Corynebacterium kroppenstedtii strain DSM 44385
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