STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPPG_09555Uncharacterized protein. (651 aa)    
Predicted Functional Partners:
SPPG_01296
Poly [ADP-ribose] polymerase.
  
 
 0.881
SPPG_08596
Poly [ADP-ribose] polymerase.
  
 
 0.869
SPPG_09466
Vezatin domain-containing protein.
    
   0.603
SPPG_00599
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
   0.603
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
     
 0.586
SPPG_07693
PCNA_C domain-containing protein.
    
   0.549
SPPG_00746
DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.
     
 0.540
SPPG_08543
Uncharacterized protein.
     
 0.536
SPPG_06431
Endo/exonuclease/phosphatase domain-containing protein.
     
 0.530
SPPG_08818
DNA excision repair protein (Rad2).
     
 0.515
Your Current Organism:
Spizellomyces punctatus
NCBI taxonomy Id: 645134
Other names: S. punctatus DAOM BR117, Spizellomyces punctatus DAOM BR117
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