STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPPG_05583E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (2182 aa)    
Predicted Functional Partners:
SPPG_06169
HECT domain-containing protein.
   
 0.998
SPPG_06286
Ubiquitin-conjugating enzyme E2 2, variant; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.955
SPPG_06227
Polyubiquitin.
   
 0.832
SPPG_03613
Polyubiquitin.
   
 0.832
SPPG_08112
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.828
SPPG_06574
RING-type domain-containing protein.
   
 0.748
SPPG_00844
Ubiquitin-like domain-containing protein.
   
 0.741
SPPG_03961
Ubiquitin-60S ribosomal protein L40.
    
  0.736
SPPG_01470
RRN7-type domain-containing protein.
    
  0.736
SPPG_01922
Homeobox domain-containing protein.
    
 
 0.724
Your Current Organism:
Spizellomyces punctatus
NCBI taxonomy Id: 645134
Other names: S. punctatus DAOM BR117, Spizellomyces punctatus DAOM BR117
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