STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPPG_030141-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (257 aa)    
Predicted Functional Partners:
SPPG_02630
Histidine biosynthesis trifunctional protein.
  
 
 0.995
SPPG_05215
Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.
  
 
 0.989
SPPG_03971
ATP phosphoribosyltransferase.
  
 
 0.989
SPPG_02291
Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family.
  
 
 0.989
SPPG_04971
Uncharacterized protein.
  
 
 0.969
SPPG_04184
Histidinol-phosphate transaminase.
  
  
 0.962
SPPG_00371
Glutamine amidotransferase type-1 domain-containing protein.
  
 
 0.943
SPPG_05282
Tryptophan synthase.
  
 
 0.901
SPPG_00784
Anthranilate phosphoribosyltransferase.
    
 0.889
SPPG_05570
GMP synthase (Glutamine-hydrolyzing) domain-containing protein.
  
 
 0.882
Your Current Organism:
Spizellomyces punctatus
NCBI taxonomy Id: 645134
Other names: S. punctatus DAOM BR117, Spizellomyces punctatus DAOM BR117
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.