STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPPG_00834DNA ligase. (914 aa)    
Predicted Functional Partners:
SPPG_00032
Ku domain-containing protein.
   
 0.984
SPPG_05936
ATP-dependent DNA helicase II, 70 kDa subunit (Ku70).
   
 0.981
SPPG_00077
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
    
 0.951
SPPG_06135
ZnF_Rad18 domain-containing protein.
   
 0.920
SPPG_09270
Uncharacterized protein.
   
 0.875
SPPG_08543
Uncharacterized protein.
  
 0.860
SPPG_03918
HIT domain-containing protein.
  
 0.854
SPPG_00780
HIT domain-containing protein.
  
 0.854
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 0.852
SPPG_07693
PCNA_C domain-containing protein.
   
 0.830
Your Current Organism:
Spizellomyces punctatus
NCBI taxonomy Id: 645134
Other names: S. punctatus DAOM BR117, Spizellomyces punctatus DAOM BR117
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