STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFF92083.1Pyruvate dehydrogenase E1 component, alpha subunit. (407 aa)    
Predicted Functional Partners:
EFF92072.1
Pyruvate dehydrogenase E1 component, beta subunit.
 0.999
EFF92084.1
Pyruvate dehydrogenase E1 component, beta subunit.
 0.999
EFF89289.1
TPP-dependent acetoin dehydrogenase complex, E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.999
EFF92085.1
Pyruvate dehydrogenase E2.
 
 0.996
EFF92073.1
Pyruvate dehydrogenase E2.
 
 0.994
EFF90632.1
Dihydrolipoyl dehydrogenase.
 
 
 0.991
EFF93039.1
Oxoglutarate dehydrogenase.
  
 0.981
EFF90634.1
Dihydrolipoyllysine-residue succinyltransferase.
 
 0.977
EFF93673.1
Alpha keto acid dehydrogenase.
 
 
 0.975
EFF94118.1
Conserved hypothetical protein.
 
 0.975
Your Current Organism:
Streptomyces sp. e14
NCBI taxonomy Id: 645465
Other names: S. sp. e14
Server load: low (30%) [HD]