STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFF92348.1RNA polymerase sigma-E factor; Belongs to the sigma-70 factor family. ECF subfamily. (179 aa)    
Predicted Functional Partners:
EFF92347.1
Lipoprotein CseA.
     
 0.858
EFF92376.1
Conserved hypothetical protein.
   
   0.855
EFF92007.1
RNA polymerase sigma-70 factor, ECF subfamily.
  
   
 0.787
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.775
EFF93000.1
Conserved hypothetical protein.
  
 
 0.771
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.760
EFF92346.1
DNA-binding response regulator.
     
 0.747
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.683
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.682
EFF91313.1
Membrane protein.
  
 
 0.668
Your Current Organism:
Streptomyces sp. e14
NCBI taxonomy Id: 645465
Other names: S. sp. e14
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.