STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFF93209.1Short-chain dehydrogenase/reductase family oxidoreductase. (229 aa)    
Predicted Functional Partners:
EFF89276.1
Non-ribosomal peptide synthetase.
  
 
 0.893
EFF94275.1
Non-ribosomal peptide synthetase MxaA; Overlaps another CDS with the same product name.
  
 
 0.872
EFF93210.1
Methionine synthase, vitamin-B12 independent.
       0.864
EFF89282.1
Non-ribosomal peptide synthetase.
    
 0.812
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
       0.810
EFF93207.1
Conserved hypothetical protein.
       0.795
EFF93629.1
long-chain-fatty-acid-CoA ligase.
   
 0.774
EFF94120.1
Polyketide synthase type I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
 0.773
EFF94126.1
Modular polyketide synthase.
  
 0.773
EFF90475.1
Glutamate synthase large subunit.
    
  0.767
Your Current Organism:
Streptomyces sp. e14
NCBI taxonomy Id: 645465
Other names: S. sp. e14
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.