STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFF93530.1Trypsin. (278 aa)    
Predicted Functional Partners:
EFF90690.1
Membrane protein.
    
 0.910
EFF92697.1
Conserved hypothetical protein.
    
 0.910
EFF93743.1
hydroxylacyl-CoA dehydrogenase.
   
 0.905
dnaK
Chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
    
 0.864
dnaK-2
Chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
    
 0.864
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.863
EFF88396.1
Copper-binding protein.
    
 0.836
sigA
RNA polymerase sigma (70) factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
     
 0.789
EFF88820.1
Integral membrane protein.
  
 
 0.744
EFF88822.1
Membrane protein; Overlaps another CDS with the same product name.
  
 
 0.717
Your Current Organism:
Streptomyces sp. e14
NCBI taxonomy Id: 645465
Other names: S. sp. e14
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.