STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFF93560.1DNA-binding protein. (357 aa)    
Predicted Functional Partners:
EFF91823.1
Integral membrane protein.
 
  0.752
EFF90647.1
Integral membrane protein.
  
   
 0.724
EFF93116.1
Cellulose-binding protein.
 
     0.719
EFF90187.1
Secreted protein.
 
  0.710
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.688
EFF91453.1
Membrane protein.
  
     0.673
rbpA
Membrane-associated GTPase; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
  
   
 0.667
EFF93466.1
Sensor histidine kinase/response regulator.
  
 
 0.654
EFF90976.1
DNA polymerase III, delta subunit.
  
     0.653
EFF93569.1
Conserved hypothetical protein.
 
     0.650
Your Current Organism:
Streptomyces sp. e14
NCBI taxonomy Id: 645465
Other names: S. sp. e14
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.