STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y2FYP5Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (916 aa)    
Predicted Functional Partners:
A0A1Y2GMN5
Kinase; Belongs to the inositol phosphokinase (IPK) family.
    
 0.789
A0A1Y2GZ82
Inositol-pentakisphosphate 2-kinase-domain-containing protein; Belongs to the tetraspanin (TM4SF) family.
     
 0.724
A0A1Y2G9M5
Kinase; Belongs to the inositol phosphokinase (IPK) family.
    
 0.644
A0A1Y2GMV3
SET domain-containing protein.
    
 0.606
A0A1Y2GZ68
SET domain-containing protein.
    
 0.606
A0A1Y2GW72
FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]
    
   0.600
A0A1Y2GD15
Uncharacterized protein.
    
 
 0.481
A0A1Y2G561
Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family.
    
   0.474
A0A1Y2GZS4
Nucleosome assembly protein-domain-containing protein; Belongs to the nucleosome assembly protein (NAP) family.
    
   0.474
A0A1Y2GIE2
High mobility group box domain-containing protein.
    
   0.463
Your Current Organism:
Lobosporangium transversale
NCBI taxonomy Id: 64571
Other names: ATCC 16960, CBS 357.67, Echinosporangium transversale, IMI 130776ii, L. transversale, NRRL 3116
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