STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y2GW12Rad51 domain-containing protein. (139 aa)    
Predicted Functional Partners:
A0A1Y2G5V5
P-loop containing nucleoside triphosphate hydrolase protein.
   
 0.996
A0A1Y2GHP1
P-loop containing nucleoside triphosphate hydrolase protein.
   
 0.996
A0A1Y2GYJ4
3'-5' exonuclease domain-containing protein.
   
 0.996
A0A1Y2GK20
Uncharacterized protein.
   
 0.992
A0A1Y2GAM4
P-loop containing nucleoside triphosphate hydrolase protein.
   
 0.991
A0A1Y2GJM1
P-loop containing nucleoside triphosphate hydrolase protein.
   
 0.988
A0A1Y2GK04
Uncharacterized protein.
   
 0.965
A0A1Y2GWB9
Uncharacterized protein.
   
 0.965
A0A1Y2G803
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
  
 0.950
A0A1Y2GEJ3
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
  
 0.921
Your Current Organism:
Lobosporangium transversale
NCBI taxonomy Id: 64571
Other names: ATCC 16960, CBS 357.67, Echinosporangium transversale, IMI 130776ii, L. transversale, NRRL 3116
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.