STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y2GYW6Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. (306 aa)    
Predicted Functional Partners:
A0A1Y2GR00
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.
   
 0.999
A0A1Y2H1C0
WD40-repeat-containing domain protein.
   
 0.998
A0A1Y2GGG4
Autophagy-related protein 3.
   
 0.991
A0A1Y2GP27
Kinase-like domain-containing protein.
    
 
 0.975
A0A1Y2GZD3
WD40-repeat-containing domain protein.
    
 0.961
A0A1Y2GH96
Autophagy-related protein.
   
 0.955
A0A1Y2GMT2
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
    
 0.916
A0A1Y2GEW2
Alpha/beta-hydrolase.
   
 
 0.898
A0A1Y2GEZ0
Alpha/Beta hydrolase protein.
   
 
 0.898
A0A1Y2GHR8
Phosphatidylinositol 3-kinase VPS34.
    
 0.844
Your Current Organism:
Lobosporangium transversale
NCBI taxonomy Id: 64571
Other names: ATCC 16960, CBS 357.67, Echinosporangium transversale, IMI 130776ii, L. transversale, NRRL 3116
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.