A0A1Y2H3C0 protein (Lobosporangium transversale)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

A0A1Y2H3C0

Uncharacterized protein. (520 aa)

Predicted Functional Partners:

A0A1Y2H0A5

0.871

A0A1Y2GDT8

0.868

A0A1Y2H0R4

0.868

A0A1Y2GH95

0.740

A0A1Y2GIF2

0.740

A0A1Y2GIJ6

0.740

A0A1Y2H1P3

0.646

A0A1Y2GJY8

0.626

A0A1Y2G6I6

0.600

A0A1Y2G8H2

0.600

Your Current Organism:

Lobosporangium transversale

NCBI taxonomy Id: 64571
Other names: ATCC 16960, CBS 357.67, Echinosporangium transversale, IMI 130776ii, L. transversale, NRRL 3116

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1Y2G6I6	A0A1Y2GDT8	P-loop containing nucleoside triphosphate hydrolase protein.	PRKCSH domain-containing protein.	0.915
A0A1Y2G6I6	A0A1Y2GH95	P-loop containing nucleoside triphosphate hydrolase protein.	Uncharacterized protein.	0.883
A0A1Y2G6I6	A0A1Y2GIF2	P-loop containing nucleoside triphosphate hydrolase protein.	Uncharacterized protein.	0.883
A0A1Y2G6I6	A0A1Y2GIJ6	P-loop containing nucleoside triphosphate hydrolase protein.	RING-type domain-containing protein.	0.883
A0A1Y2G6I6	A0A1Y2GJY8	P-loop containing nucleoside triphosphate hydrolase protein.	RING-type domain-containing protein.	0.637
A0A1Y2G6I6	A0A1Y2H0A5	P-loop containing nucleoside triphosphate hydrolase protein.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.929
A0A1Y2G6I6	A0A1Y2H0R4	P-loop containing nucleoside triphosphate hydrolase protein.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.917
A0A1Y2G6I6	A0A1Y2H3C0	P-loop containing nucleoside triphosphate hydrolase protein.	Uncharacterized protein.	0.600
A0A1Y2G8H2	A0A1Y2GDT8	Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family.	PRKCSH domain-containing protein.	0.938
A0A1Y2G8H2	A0A1Y2GH95	Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.883
A0A1Y2G8H2	A0A1Y2GIF2	Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.883
A0A1Y2G8H2	A0A1Y2GIJ6	Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family.	RING-type domain-containing protein.	0.936
A0A1Y2G8H2	A0A1Y2GJY8	Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family.	RING-type domain-containing protein.	0.637
A0A1Y2G8H2	A0A1Y2H0A5	Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.938
A0A1Y2G8H2	A0A1Y2H0R4	Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.933
A0A1Y2G8H2	A0A1Y2H3C0	Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.600
A0A1Y2GDT8	A0A1Y2G6I6	PRKCSH domain-containing protein.	P-loop containing nucleoside triphosphate hydrolase protein.	0.915
A0A1Y2GDT8	A0A1Y2G8H2	PRKCSH domain-containing protein.	Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family.	0.938
A0A1Y2GDT8	A0A1Y2GH95	PRKCSH domain-containing protein.	Uncharacterized protein.	0.940
A0A1Y2GDT8	A0A1Y2GIF2	PRKCSH domain-containing protein.	Uncharacterized protein.	0.940

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

32

average node degree:

5.82

avg. local clustering coefficient:

0.438

expected number of edges:

10

PPI enrichment p-value:

3.58e-08

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0050660

Flavin adenine dinucleotide binding

8 of 57

1.69

3.25

2.57e-10

GO:0009055

Electron transfer activity

9 of 75

1.62

3.21

2.96e-11

GO:0016491

Oxidoreductase activity

11 of 420

0.96

1.15

8.03e-09

GO:0043167

Ion binding

10 of 1117

0.49

0.37

0.0070

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

11 of 1289

0.47

0.39

0.00093

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1846

Electron transfer flavoprotein domain, and Acyl-CoA dehydrogenase, conserved site

10 of 25

2.14

6.77

9.77e-18

CL:1848

Electron transfer flavoprotein domain, and Acyl-CoA dehydrogenase, conserved site

9 of 18

2.24

6.73

2.37e-16

CL:1851

Electron transfer flavoprotein domain, and Fatty acid beta-oxidation, unsaturated, even number

8 of 13

2.33

6.45

8.71e-15

CL:1853

Electron transfer flavoprotein, alpha/beta-subunit, N-terminal

3 of 5

2.32

2.11

9.64e-05

CL:1867

Electron transfer flavoprotein domain

2 of 5

2.14

0.99

0.0138

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005759

Mitochondrial matrix

7 of 11

2.34

5.75

6.80e-13

GOCC:0005739

Mitochondrion

9 of 49

1.8

4.23

3.71e-13

GOCC:0043231

Intracellular membrane-bounded organelle

10 of 202

1.23

1.91

1.21e-10

GOCC:0005737

Cytoplasm

10 of 1016

0.53

0.44

0.00048

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00766

Electron transfer flavoprotein FAD-binding domain

7 of 7

2.54

6.25

2.99e-13

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR001308

Electron transfer flavoprotein alpha subunit/FixB

7 of 7

2.54

6.07

7.61e-13

IPR014730

Electron transfer flavoprotein, alpha/beta-subunit, N-terminal

7 of 12

2.31

5.31

5.56e-12

IPR014731

Electron transfer flavoprotein, alpha subunit, C-terminal

6 of 6

2.54

5.23

5.21e-11

IPR029035

DHS-like NAD/FAD-binding domain superfamily

6 of 11

2.28

4.46

5.20e-10

IPR014729

Rossmann-like alpha/beta/alpha sandwich fold

7 of 61

1.6

2.56

4.09e-08

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00893

Electron transfer flavoprotein domain

8 of 14

2.3

6.43

5.74e-15

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (18%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About