STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdxHPyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (216 aa)    
Predicted Functional Partners:
pdxJ
Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
  
  
 0.952
SMB99242.1
KEGG: mxa:MXAN_6687 hypothetical protein.
       0.714
SMB97356.1
Carbamoyl-phosphate synthase large subunit; InterPro IPR005483:IPR003135:IPR005479:IPR011607:IPR005480:IPR0054 81:IPR011761:IPR006275; COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); KEGG: cad; carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; K11540 carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase; SPTR: A5ZC56 Putative uncharacterized protein; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; MGS domain protein; Carbamoyl-pho [...]
 
 
  
 0.604
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family.
    
 0.595
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
    
 0.581
SMB99233.1
Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
       0.568
SMB99236.1
InterPro IPR008323; COGs: COG4198 conserved hypothetical protein; KEGG: afw:Anae109_1414 hypothetical protein; SPTR: A3HTK6 Putative uncharacterized protein; PFAM: conserved hypothetical protein.
       0.548
SMB99243.1
Protein of unknown function DUF179; InterPro IPR003774; COGs: COG1678 Putative transcriptional regulator protein; KEGG: hha:Hhal_0938 hypothetical protein; SPTR: A1ZFZ1 Putative uncharacterized protein; PFAM: protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family.
  
    0.517
gcvP
Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
 
   
 0.466
carA
Carbamoyl-phosphate synthase small subunit; InterPro IPR006220:IPR011702:IPR001317:IPR002474:IPR000991:IPR0062 74; COGs: COG0505 Carbamoylphosphate synthase small subunit; KEGG: hypothetical protein; SPTR: A5ZC55 Putative uncharacterized protein; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family.
 
      0.411
Your Current Organism:
Hymenobacter roseosalivarius
NCBI taxonomy Id: 645990
Other names: H. roseosalivarius DSM 11622, Hymenobacter roseosalivarius AA-718, Hymenobacter roseosalivarius DSM 11622, Hymenobacter roseosalivarius str. DSM 11622, Hymenobacter roseosalivarius strain DSM 11622
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