STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB97262.1Metallophosphoesterase; KEGG: glo:Glov_2375 5'-nucleotidase domain protein; SPTR: A2TT00 Possible secreted 5'-nucleotidase; PFAM: metallophosphoesterase; InterPro IPR006179:IPR004843:IPR006146:IPR006311; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; Belongs to the 5'-nucleotidase family. (309 aa)    
Predicted Functional Partners:
SMB97258.1
5'-Nucleotidase domain protein; InterPro IPR006179:IPR008334:IPR001412; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; KEGG: psa:PST_4140 5'-nucleotidase; SPTR: A5ZBW0 Putative uncharacterized protein; PFAM: 5'-Nucleotidase domain protein.
  
  0.992
tdk
Thymidine kinase; InterPro IPR001267; COGs: COG1435 Thymidine kinase; KEGG: hypothetical protein; SPTR: A1ZXX9 Thymidine kinase; PFAM: thymidine kinase; PRIAM: Thymidine kinase.
 
  
  0.872
SMC00281.1
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
 
  
  0.869
SMB96717.1
InterPro IPR006082:IPR000764:IPR006083; COGs: COG0572 Uridine kinase; KEGG: mxa:MXAN_4159 uridine kinase; SPTR: A3HVM0 Uridine kinase; PFAM: phosphoribulokinase/uridine kinase; Belongs to the uridine kinase family.
  
 
 0.868
SMC00254.1
Competence/damage-inducible protein cinA; InterPro IPR001453:IPR008136:IPR008135; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; KEGG: dal:Dalk_4012 competence/damage-inducible protein CinA; SPTR: A1ZUS5 Competence-damage inducible protein; PFAM: CinA domain protein; molybdopterin binding domain; TIGRFAM: competence/damage-inducible protein CinA.
   
 
  0.865
SMB95138.1
Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). Belongs to the OMP decarboxylase family. Type 2 subfamily.
    
 0.865
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.864
SMB89618.1
InterPro IPR000836; COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; KEGG: hypoxanthine-guanine phosphoribosyltransferase; SPTR: A5ZKY5 Putative uncharacterized protein; PFAM: phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase.
  
  
 0.863
SMB91130.1
Inosine guanosine and xanthosine phosphorylase family; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.861
surE
3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.861
Your Current Organism:
Hymenobacter roseosalivarius
NCBI taxonomy Id: 645990
Other names: H. roseosalivarius DSM 11622, Hymenobacter roseosalivarius AA-718, Hymenobacter roseosalivarius DSM 11622, Hymenobacter roseosalivarius str. DSM 11622, Hymenobacter roseosalivarius strain DSM 11622
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.