STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB97278.1Site-2 protease. Metallo peptidase. MEROPS family M50B; InterPro IPR001478:IPR008915:IPR004387; COGs: COG0750 membrane-associated Zn-dependent protease 1; KEGG: pca:Pcar_1914 putative membrane-associated Zn-dependent protease; SPTR: A3HWK9 Membrane-associated zinc metalloprotease; SMART: PDZ/DHR/GLGF domain protein; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; TIGRFAM: membrane-associated zinc metalloprotease. (433 aa)    
Predicted Functional Partners:
dxr
1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.
 
  
 0.845
SMB97654.1
Signal peptidase I; InterPro IPR000223:IPR011056; COGs: COG0681 Signal peptidase I; KEGG: pca:Pcar_1617 signal peptidase I; SPTR: A3HZF4 Signal peptidase I; PFAM: peptidase S24 and S26 domain protein; TIGRFAM: signal peptidase I; Belongs to the peptidase S26 family.
 
  
 0.746
SMB86519.1
Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
  
  
 0.732
SMB86530.1
Beta-barrel assembly machine subunit BamA; InterPro IPR000184:IPR010827:IPR016474; COGs: COG4775 Outer membrane protein/protective antigen OMA87; KEGG: gme:Gmet_2357 surface antigen (D15); SPTR: A1ZP33 Bacterial surface antigen family protein; PFAM: surface antigen (D15); surface antigen variable number repeat protein; TIGRFAM: outer membrane protein assembly complex, YaeT protein.
 
  
 0.681
SMB91488.1
Cell cycle protein; InterPro IPR001182; COGs: COG0772 Bacterial cell division membrane protein; KEGG: bha:BH3276 stage V sporulation protein E; SPTR: A3HXN9 Putative transmembrane rod-shape determining protein; PFAM: cell cycle protein; Belongs to the SEDS family.
 
    0.680
yidC
60 kDa inner membrane insertion protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
 
    0.668
ftsA
Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
  
    0.640
SMB91452.1
Peptidoglycan glycosyltransferase; SMART: PASTA domain containing protein; PFAM: penicillin-binding protein transpeptidase; PASTA domain containing protein; Penicillin-binding protein dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; KEGG: gsu:GSU3075 penicillin-binding protein; SPTR: A3HXP3 Penicillin-binding protein; InterPro IPR001460:IPR005543:IPR005311.
 
  
 0.631
murG
UDP-N-acetylglucosamine-N- acetylmuramylpentapeptide N-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
 
    0.611
SMB96476.1
Protease Do; InterPro IPR001940:IPR001254:IPR001478:IPR011782; COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; KEGG: mex:Mext_3827 protease Do; SPTR: A3HWK1 Serine protease; SMART: PDZ/DHR/GLGF domain protein; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; TIGRFAM: protease Do.
 
   
 0.602
Your Current Organism:
Hymenobacter roseosalivarius
NCBI taxonomy Id: 645990
Other names: H. roseosalivarius DSM 11622, Hymenobacter roseosalivarius AA-718, Hymenobacter roseosalivarius DSM 11622, Hymenobacter roseosalivarius str. DSM 11622, Hymenobacter roseosalivarius strain DSM 11622
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