STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB96055.1Shikimate dehydrogenase; InterPro IPR013708:IPR006151; COGs: COG0169 Shikimate 5-dehydrogenase; KEGG: bha:BH1324 shikimate 5-dehydrogenase; SPTR: A4CQ38 Putative shikimate 5-dehydrogenase; PFAM: Shikimate dehydrogenase substrate binding domain protein; Shikimate/quinate 5-dehydrogenase. (246 aa)    
Predicted Functional Partners:
SMB90076.1
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
 0.984
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 0.969
SMB90067.1
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
 0.968
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
 
 
 0.955
aroQ
3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
 
 
 0.949
SMB90065.1
3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; InterPro IPR006218:IPR002701; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; KEGG: sdn:Sden_0622 DAHP synthetase I/KdsA; SPTR: A1ZR43 Phospho-2-dehydro-3-deoxyheptonate aldolase/chorismate mutase; PFAM: DAHP synthetase I/KDSA; Chorismate mutase.
 
 
 0.938
SMB83060.1
3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; InterPro IPR006218:IPR002701; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; KEGG: sdn:Sden_0622 DAHP synthetase I/KdsA; SPTR: A5ZFE1 Putative uncharacterized protein; PFAM: DAHP synthetase I/KDSA; Chorismate mutase.
 
 
 0.937
SMB86436.1
Anthranilate synthase, component II; InterPro IPR006220:IPR011702:IPR001317:IPR000991:IPR006221; COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; KEGG: rme:Rmet_3179 anthranilate synthase component II; SPTR: A3HW41 Anthranilate synthase component II; PFAM: glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase.
 
 0.793
SMC00511.1
Anthranilate synthase, component II; InterPro IPR006220:IPR011702:IPR001317:IPR000991:IPR006221; COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; KEGG: pnu:Pnuc_0147 glutamine amidotransferase of anthranilate synthase; SPTR: A3HZI1 Anthranilate synthase component II; PFAM: glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase.
 
 0.780
SMB96192.1
Nicotinate-nucleotide adenylyltransferase; InterPro IPR004820:IPR005248; COGs: COG1057 Nicotinic acid mononucleotide adenylyltransferase; KEGG: bha:BH1326 nicotinate-nucleotide adenylyltransferase; SPTR: Q11XI1 Probable nicotinate-nucleotide adenylyltransferase; PFAM: cytidylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase.
 
  
 0.774
Your Current Organism:
Hymenobacter roseosalivarius
NCBI taxonomy Id: 645990
Other names: H. roseosalivarius DSM 11622, Hymenobacter roseosalivarius AA-718, Hymenobacter roseosalivarius DSM 11622, Hymenobacter roseosalivarius str. DSM 11622, Hymenobacter roseosalivarius strain DSM 11622
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