STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB84143.1HSP20 family protein; InterPro IPR002068; KEGG: csa:Csal_1429 heat shock protein HSP20; SPTR: A1ZSR2 Putative uncharacterized protein; Belongs to the small heat shock protein (HSP20) family. (126 aa)    
Predicted Functional Partners:
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.686
SMB90098.1
ATPase AAA-2 domain protein; InterPro IPR001270:IPR001943:IPR003959:IPR013093:IPR011704:IPR0041 76:IPR003593; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; KEGG: bsu:BSU00860 class III stress response-related ATPase; SPTR: A3HZ66 ATPase; SMART: AAA ATPase; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; ATPase associated with various cellular activities AAA_5; Clp domain protein; Belongs to the ClpA/ClpB family.
  
 
 0.686
SMB85577.1
ATP-binding region ATPase domain protein; Molecular chaperone. Has ATPase activity.
  
 
 0.538
SMB84154.1
Hypothetical protein; SPTR: A1ZJ51 Putative uncharacterized protein.
       0.463
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
  
 0.413
SMB92386.1
Serine/threonine protein kinase; InterPro IPR001245:IPR002290:IPR000719; COGs: COG0515 Serine/threonine protein kinase; SPTR: B7U1M7 Cold-induced CIPK; SMART: serine/threonine protein kinase; tyrosine protein kinase; PFAM: tyrosine protein kinase; KEGG: aca:ACP_1251 non-specific serine/threonine protein kinase.
   
 
 0.410
Your Current Organism:
Hymenobacter roseosalivarius
NCBI taxonomy Id: 645990
Other names: H. roseosalivarius DSM 11622, Hymenobacter roseosalivarius AA-718, Hymenobacter roseosalivarius DSM 11622, Hymenobacter roseosalivarius str. DSM 11622, Hymenobacter roseosalivarius strain DSM 11622
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.