STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB89737.1Iron-sulfur cluster assembly accessory protein; InterPro IPR000361:IPR017870:IPR016092; COGs: COG0316 conserved hypothetical protein; KEGG: aba:Acid345_1581 HesB/YadR/YfhF; SPTR: A3I0T1 Iron-sulfur cluster assembly accessory protein, putative; PFAM: HesB/YadR/YfhF-family protein; TIGRFAM: iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family. (117 aa)    
Predicted Functional Partners:
SMB91281.1
Co-chaperone Hsc20; InterPro IPR009073:IPR001623:IPR004640; KEGG: mfa:Mfla_0805 co-chaperone Hsc20; SPTR: A0XZ08 Co-chaperone HscB; PFAM: HSC20 oligomerisation; heat shock protein DnaJ domain protein; TIGRFAM: co-chaperone Hsc20.
 
 
 0.890
SMB98194.1
FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
  
 0.778
iscS
Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
 
  
 0.663
prfA
Bacterial peptide chain release factor 1 (bRF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
     
 0.655
SMB86658.1
Cysteine desulfurase; InterPro IPR000192; COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; KEGG: hypothetical protein; SPTR: A1ZLW7 Iron-sulfur cofactor synthesis; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase.
 
  
 0.634
SMB94660.1
Rieske [2Fe-2S] domain protein; InterPro IPR005806; KEGG: glo:Glov_0473 Rieske (2Fe-2S) domain protein; SPTR: A0CYB1 Chromosome undetermined scaffold_31, whole genome shotgun sequence; PFAM: Rieske [2Fe-2S] domain protein.
  
 
 0.563
SMB87447.1
Ferredoxin; InterPro IPR001055:IPR001041; COGs: COG0633 Ferredoxin; KEGG: hiq:CGSHiGG_04670 hypothetical protein; SPTR: A4NVW1 Ferredoxin, 2Fe-2S; PFAM: ferredoxin.
 
 
 0.550
SMC00217.1
Cobyrinic acid ac-diamide synthase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
 
 
 
 0.545
SMB89749.1
Hypothetical protein; SPTR: A3I0T0 Putative uncharacterized protein.
       0.541
SMB89323.1
InterPro IPR002130:IPR004155:IPR000357; COGs: COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; KEGG: mxa:MXAN_4676 peptidylprolyl cis-trans isomerase, cyclophilin-type; SPTR: A1ZMW4 Peptidyl-prolyl cis-trans isomerase, cyclophilin-type domain protein; SMART: PBS lyase HEAT domain protein repeat-containing protein; PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; PBS lyase HEAT domain protein repeat-containing protein; HEAT domain containing protein.
    
 
 0.512
Your Current Organism:
Hymenobacter roseosalivarius
NCBI taxonomy Id: 645990
Other names: H. roseosalivarius DSM 11622, Hymenobacter roseosalivarius AA-718, Hymenobacter roseosalivarius DSM 11622, Hymenobacter roseosalivarius str. DSM 11622, Hymenobacter roseosalivarius strain DSM 11622
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