STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iscSCysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. (404 aa)    
Predicted Functional Partners:
SMB98194.1
FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
 
 0.999
SMB87447.1
Ferredoxin; InterPro IPR001055:IPR001041; COGs: COG0633 Ferredoxin; KEGG: hiq:CGSHiGG_04670 hypothetical protein; SPTR: A4NVW1 Ferredoxin, 2Fe-2S; PFAM: ferredoxin.
 
 0.959
SMB84771.1
UBA/THIF-type NAD/FAD binding protein; InterPro IPR007901:IPR000594:IPR001763:IPR001307; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; KEGG: cbc:CbuK_0743 molybdopterin biosynthesis MoeB protein; SPTR: A1ZVV1 Molybdopterin biosynthesis protein; SMART: Rhodanese domain protein; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein.
   
 0.937
selD
Selenophosphate synthase; Synthesizes selenophosphate from selenide and ATP.
   
 0.926
SMB87581.1
Ferredoxin; InterPro IPR001041; COGs: COG0633 Ferredoxin; KEGG: sil:SPO0901 adenylate/guanylate cyclase; SPTR: A3HY64 Ferredoxin; PFAM: ferredoxin.
 
 0.889
SMB91281.1
Co-chaperone Hsc20; InterPro IPR009073:IPR001623:IPR004640; KEGG: mfa:Mfla_0805 co-chaperone Hsc20; SPTR: A0XZ08 Co-chaperone HscB; PFAM: HSC20 oligomerisation; heat shock protein DnaJ domain protein; TIGRFAM: co-chaperone Hsc20.
 
 
 0.871
SMB86658.1
Cysteine desulfurase; InterPro IPR000192; COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; KEGG: hypothetical protein; SPTR: A1ZLW7 Iron-sulfur cofactor synthesis; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase.
  
  
 
0.870
SMB96831.1
Ferredoxin; InterPro IPR001041; KEGG: adrenodoxin precursor; SPTR: A3HWM2 Ferredoxin; PFAM: ferredoxin.
  
 0.867
SMB98193.1
Iron-sulfur cluster assembly accessory protein; InterPro IPR000361:IPR017870:IPR016092; COGs: COG0316 conserved hypothetical protein; KEGG: bba:Bd1193 scaffold protein for iron-sulfur cluster assembly; SPTR: A1ZYI9 Scaffold protein for iron-sulfur cluster assembly; PFAM: HesB/YadR/YfhF-family protein; TIGRFAM: iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family.
 
  
 0.767
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
    
 
 0.669
Your Current Organism:
Hymenobacter roseosalivarius
NCBI taxonomy Id: 645990
Other names: H. roseosalivarius DSM 11622, Hymenobacter roseosalivarius AA-718, Hymenobacter roseosalivarius DSM 11622, Hymenobacter roseosalivarius str. DSM 11622, Hymenobacter roseosalivarius strain DSM 11622
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.