STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB98255.123S rRNA m(5)U-1939 methyltransferase; InterPro IPR010280:IPR002792:IPR001566; COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; KEGG: dat:HRM2_26600 TrmA; SPTR: A3I0Q4 Putative RNA methyltransferase; PFAM: (Uracil-5)-methyltransferase; TIGRFAM: RNA methyltransferase, TrmA family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (493 aa)    
Predicted Functional Partners:
SMB99233.1
Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
     0.726
SMB98253.1
Excinuclease ABC C subunit domain protein; InterPro IPR000305; COGs: COG2827 endonuclease containing a URI domain; KEGG: aca:ACP_0799 putative excinuclease ABC; SPTR: A1ZTH3 Excinuclease ABC, C subunit, N-terminal; SMART: Excinuclease ABC C subunit domain protein; PFAM: Excinuclease ABC C subunit domain protein.
  
    0.568
SMB98256.1
Short-chain dehydrogenase/reductase SDR; InterPro IPR002347:IPR002424:IPR002198:IPR013968; COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; KEGG: mxa:MXAN_0817 short chain dehydrogenase; SPTR: A1ZIV8 Short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.556
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
 
  
 0.512
SMB81809.1
tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
 
  
 0.483
SMB98251.1
Hypothetical protein; SPTR: A3I0Q5 Putative uncharacterized protein.
       0.460
SMB97816.1
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     0.446
SMB87167.1
InterPro IPR010456; COGs: COG2264 Ribosomal protein L11 methylase; KEGG: hypothetical protein; SPTR: A4CM81 Ribosomal protein L11 methyltransferase; PFAM: ribosomal L11 methyltransferase.
 
   
 0.427
Your Current Organism:
Hymenobacter roseosalivarius
NCBI taxonomy Id: 645990
Other names: H. roseosalivarius DSM 11622, Hymenobacter roseosalivarius AA-718, Hymenobacter roseosalivarius DSM 11622, Hymenobacter roseosalivarius str. DSM 11622, Hymenobacter roseosalivarius strain DSM 11622
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.