STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gmhAPhosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily. (194 aa)    
Predicted Functional Partners:
SMB90973.1
PfkB domain protein; InterPro IPR011611:IPR002173; COGs: COG2870 ADP-heptose synthase bifunctional sugar kinase/adenylyltransferase; KEGG: gdj:Gdia_1846 RfaE bifunctional protein; SPTR: A1ZNS2 Bifunctional protein HldE; PFAM: PfkB domain protein.
  
 0.990
SMB82238.1
rfaE bifunctional protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
  
 0.985
SMB97870.1
D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase; InterPro IPR005834:IPR013954:IPR006543:IPR006549; COGs: COG0241 Histidinol phosphatase and related phosphatase; KEGG: dds:Ddes_1837 D,D-heptose 1,7-bisphosphate phosphatase; SPTR: A1ZZD7 D,D-heptose 1,7-bisphosphate phosphatase; PFAM: Polynucleotide kinase 3 phosphatase central region; Haloacid dehalogenase domain protein hydrolase; TIGRFAM: hydrolase, HAD-superfamily, subfamily IIIA; histidinol-phosphate phosphatase family protein; Belongs to the gmhB family.
 
 0.981
hisB
Imidazoleglycerol-phosphate dehydratase; InterPro IPR000807:IPR013954:IPR006543:IPR005954:IPR006549; COGs: COG0131 Imidazoleglycerol-phosphate dehydratase; KEGG: sml:Smlt2165 putative imidazoleglycerol-phosphate dehydratase; histidinol phosphatase; SPTR: A3HTQ9 Imidazole glycerol-phosphate dehydratase/histidinol phosphatase; PFAM: imidazoleglycerol-phosphate dehydratase; Polynucleotide kinase 3 phosphatase central region; PRIAM: Histidinol-phosphatase; TIGRFAM: histidinol-phosphatase; histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; In the C- [...]
  
 
 0.871
SMB87282.1
KEGG: hypothetical protein; SPTR: B6SUZ1 Putative uncharacterized protein.
       0.773
SMB97054.1
Glycosyl transferase family 9; InterPro IPR002201; COGs: COG0859 ADP-heptose:LPS heptosyltransferase; SPTR: A1ZR66 Heptosyltransferase; PFAM: glycosyl transferase family 9; KEGG: ank:AnaeK_2700 lipopolysaccharide heptosyltransferase II.
 
  
 0.716
hldD
ADP-glyceromanno-heptose 6-epimerase precursor; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
 
  
 0.676
SMB96168.1
Glycosyl transferase family 9; InterPro IPR002201; COGs: COG0859 ADP-heptose:LPS heptosyltransferase; KEGG: reu:Reut_A2559 glycosyl transferase family protein; SPTR: A1ZR65 Glycosyl transferase, family 9; PFAM: glycosyl transferase family 9.
 
  
 0.638
SMB96941.1
Glycosyl transferase family 9; InterPro IPR002201; COGs: COG0859 ADP-heptose:LPS heptosyltransferase; KEGG: lip:LI0698 ADP-heptose:LPS heptosyltransferase II; SPTR: A1ZMY2 Lipopolysaccharide heptosyltransferase II, putative; PFAM: glycosyl transferase family 9.
 
  
 0.614
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
    
 
 0.583
Your Current Organism:
Hymenobacter roseosalivarius
NCBI taxonomy Id: 645990
Other names: H. roseosalivarius DSM 11622, Hymenobacter roseosalivarius AA-718, Hymenobacter roseosalivarius DSM 11622, Hymenobacter roseosalivarius str. DSM 11622, Hymenobacter roseosalivarius strain DSM 11622
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.