STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMC00222.1KEGG: mch:Mchl_3369 hypothetical protein. (187 aa)    
Predicted Functional Partners:
SMB98473.1
Multi-sensor hybrid histidine kinase; InterPro IPR004358:IPR003018:IPR013656:IPR013767:IPR003594:IPR0036 61:IPR008207:IPR001789:IPR001610:IPR000014:IPR000700:IPR0 05467; COGs: COG0642 Signal transduction histidine kinase; KEGG: gsu:GSU2314 sensory box histidine kinase/response regulator; SPTR: A1ZKB7 Sensor protein; SMART: response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; GAF domain protein; ATP-binding region ATPase domain protein; PAS domain containing protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; GA [...]
 
 0.976
SMC00221.1
PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; InterPro IPR013154:IPR013149:IPR002328; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; KEGG: mch:Mchl_3368 alcohol dehydrogenase GroES domain protein; SPTR: A0YVV1 Alcohol dehydrogenase.
     0.934
SMB93608.1
Putative PAS/PAC sensor protein; InterPro IPR013656:IPR000014:IPR000700; KEGG: azo:azo1544 GGDEF/EAL/PAC/PAS-domain-containing protein; SPTR: A3J744 Sensor protein; SMART: PAS domain containing protein; PFAM: PAS fold-4 domain protein; TIGRFAM: PAS sensor protein.
   
 0.913
SMB98154.1
Multi-sensor hybrid histidine kinase; InterPro IPR004358:IPR013655:IPR001789:IPR013767:IPR013656:IPR0035 94:IPR003661:IPR001610:IPR000014:IPR008207:IPR000700:IPR0 05467; COGs: COG0642 Signal transduction histidine kinase; KEGG: tdn:Suden_0219 multi-sensor hybrid histidine kinase; SPTR: A3HWD5 Sensor protein; SMART: response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; ATP-binding region ATPase domain protein; PFAM: response regulator receiver; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain pr [...]
   
 0.913
SMB79968.1
PAS/PAC sensor hybrid histidine kinase; InterPro IPR004358:IPR013655:IPR001789:IPR013656:IPR013767:IPR0035 94:IPR003661:IPR001610:IPR000014:IPR000700:IPR005467; COGs: COG0642 Signal transduction histidine kinase; KEGG: cak:Caul_0720 multi-sensor hybrid histidine kinase; SPTR: A4BZQ5 Sensor protein; SMART: response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; ATP-binding region ATPase domain protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; PAS fold-4 do [...]
   
 0.913
SMC00669.1
Putative sensor with HAMP domain; InterPro IPR003660; KEGG: bja:bll2599 two-component hybrid sensor and regulator; SPTR: A1YBU7 Sensor protein (Fragment); SMART: histidine kinase HAMP region domain protein; PFAM: histidine kinase HAMP region domain protein.
   
 0.856
SMB91900.1
PAS/PAC sensor signal transduction histidine kinase; InterPro IPR004358:IPR013655:IPR013767:IPR003594:IPR013656:IPR0016 10:IPR000014:IPR000700:IPR005467; COGs: COG4585 Signal transduction histidine kinase; KEGG: reh:H16_A1985 signal transduction histidine kinase containing PAS/PAC sensor domain; SPTR: A1ZEE5 Multi-sensor Hybrid Histidine Kinase, putative; SMART: ATP-binding region ATPase domain protein; PAC repeat-containing protein; PAS domain containing protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain prote [...]
  
 0.836
SMB95744.1
Transcriptional regulator, LytTR family; InterPro IPR007492:IPR003018; COGs: COG3279 Response regulator of the LytR/AlgR family; KEGG: amc:MADE_03205 histidine kinase response regulator hybrid protein; SPTR: A0ZB66 Sensor protein; SMART: GAF domain protein; PFAM: LytTr DNA-binding region; GAF domain protein.
  
 0.788
SMB99323.1
Two component transcriptional regulator, AraC family; InterProIPR000005:IPR004358:IPR001761:IPR001789:IPR 003594:IPR003661:IPR005467; COGs: COG1879 ABC-type sugar transport system periplasmic component; KEGG: pat:Patl_1836 two component AraC family transcriptional regulator; SPTR: A5ZIK5 Sensor protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; helix-turn-helix- domain containing protein AraC type; histidine kinase A domain protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; periplasmic binding protein/LacI transcrip [...]
 
 0.767
SMB82026.1
PAS/PAC sensor signal transduction histidine kinase; InterPro IPR004358:IPR013656:IPR003594:IPR000700:IPR005467; COGs: COG0642 Signal transduction histidine kinase; KEGG: scl:sce0206 two-component system sensor histidine kinase/response regulator, hybrid ('one-component system'); SPTR: A1ZIZ7 Sensor protein; SMART: ATP-binding region ATPase domain protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein.
 
 0.749
Your Current Organism:
Hymenobacter roseosalivarius
NCBI taxonomy Id: 645990
Other names: H. roseosalivarius DSM 11622, Hymenobacter roseosalivarius AA-718, Hymenobacter roseosalivarius DSM 11622, Hymenobacter roseosalivarius str. DSM 11622, Hymenobacter roseosalivarius strain DSM 11622
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