STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
lpxC3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. (464 aa)    
Predicted Functional Partners:
SMC00249.1
acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
 0.999
lpxD
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
 
 0.993
SMB89221.1
3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 0.970
SMB91714.1
[Acyl-carrier-protein] S-malonyltransferase; InterPro IPR014043:IPR004410; COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; KEGG: hap:HAPS_0853 malonyl CoA-acyl carrier protein transacylase (MCT); SPTR: A1ZI66 Malonyl CoA-acyl carrier protein transacylase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase.
 
 
 0.964
SMB93039.1
Beta-ketoacyl synthase; InterPro IPR014031:IPR014030; COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; KEGG: oca:OCAR_6484 3-oxoacyl-[acyl-carrier-protein] synthase 2; SPTR: A4CIS7 Beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.954
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 0.945
SMB86008.1
InterPro IPR006163; KEGG: hypothetical protein; SPTR: A3JIG1 Acyl carrier protein.
  
 0.945
accD
acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
 
 
 0.940
SMC00376.1
acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 
 0.935
SMB89866.1
Enoyl-[acyl-carrier-protein] reductase [NADH]; COGs: COG0623 Enoyl-(acyl-carrier-protein); KEGG: sit:TM1040_1147 enoyl-(acyl carrier protein) reductase; SPTR: A3HXA2 Enoyl-[acyl-carrier-protein] reductase; PRIAM: Enoyl-[acyl-carrier-protein] reductase (NADH).
  
 
 0.931
Your Current Organism:
Hymenobacter roseosalivarius
NCBI taxonomy Id: 645990
Other names: H. roseosalivarius DSM 11622, Hymenobacter roseosalivarius AA-718, Hymenobacter roseosalivarius DSM 11622, Hymenobacter roseosalivarius str. DSM 11622, Hymenobacter roseosalivarius strain DSM 11622
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.