STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB94158.1Pentapeptide repeat protein; InterPro IPR001646; COGs: COG1357 Uncharacterized low-complexity protein; KEGG: dps:DP0533 MCBG protein (microcin resistance protein); SPTR: A1ZFK8 Antibiotic resistance protein McbG; PFAM: pentapeptide repeat protein. (200 aa)    
Predicted Functional Partners:
SMB99924.1
InterPro IPR001241:IPR006171:IPR003594:IPR013506; COGs: COG0187 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) B subunit; KEGG: dps:DP2280 DNA topoisomerase IV subunit B; SPTR: A3HSD7 DNA topoisomerase IV subunit B; SMART: DNA topoisomerase II; ATP-binding region ATPase domain protein; PFAM: DNA topoisomerase type IIA subunit B region 2 domain protein; ATP-binding region ATPase domain protein; TOPRIM domain protein.
   
 
 0.779
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.778
SMB94176.1
Patatin; InterPro IPR002641; COGs: COG1752 esterase of the alpha-beta hydrolase superfamily; KEGG: pag:PLES_17251 hypothetical protein; SPTR: A5ZCG6 Putative uncharacterized protein; PFAM: Patatin.
     
 0.682
SMB98473.1
Multi-sensor hybrid histidine kinase; InterPro IPR004358:IPR003018:IPR013656:IPR013767:IPR003594:IPR0036 61:IPR008207:IPR001789:IPR001610:IPR000014:IPR000700:IPR0 05467; COGs: COG0642 Signal transduction histidine kinase; KEGG: gsu:GSU2314 sensory box histidine kinase/response regulator; SPTR: A1ZKB7 Sensor protein; SMART: response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; GAF domain protein; ATP-binding region ATPase domain protein; PAS domain containing protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; GA [...]
  
 0.643
SMB94869.1
KEGG: sun:SUN_1623 hypothetical protein.
   
 
 0.562
SMB89193.1
Pyruvate kinase; InterPro IPR015793:IPR015794:IPR001697; COGs: COG0469 Pyruvate kinase; KEGG: gbm:Gbem_1182 pyruvate kinase; SPTR: A1ZI48 Pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PRIAM: Pyruvate kinase; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
    
  0.557
SMC00494.1
KEGG: acp:A2cp1_1592 hypothetical protein; SPTR: A4CNE8 Lipoprotein, putative.
    
   0.551
SMB85082.1
KEGG: eli:ELI_13110 hypothetical protein; SPTR: Q46EG9 Putative uncharacterized protein.
    
   0.551
SMB82128.1
OmpA/MotB domain protein; InterPro IPR001035:IPR006664:IPR006665:IPR011659:IPR013026; COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; KEGG: hypothetical protein; K03640 peptidoglycan-associated lipoprotein; SPTR: A3HXW3 OmpA family protein; PFAM: OmpA/MotB domain protein; WD40 domain protein beta Propeller.
  
 
 0.550
SMB94327.1
Hypothetical protein; KEGG: azc:AZC_0416 putative signaling protein; SPTR: A3TSF0 Two-component sensor histidine kinase.
     
 0.545
Your Current Organism:
Hymenobacter roseosalivarius
NCBI taxonomy Id: 645990
Other names: H. roseosalivarius DSM 11622, Hymenobacter roseosalivarius AA-718, Hymenobacter roseosalivarius DSM 11622, Hymenobacter roseosalivarius str. DSM 11622, Hymenobacter roseosalivarius strain DSM 11622
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.