STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB94245.1InterPro IPR002202; COGs: COG1257 Hydroxymethylglutaryl-CoA reductase; KEGG: sus:Acid_5728 3-hydroxy-3-methylglutaryl-coenzyme A reductase; PFAM: hydroxymethylglutaryl-coenzyme A reductase; PRIAM: Hydroxymethylglutaryl-CoA reductase (NADPH); SPTR: A1ZFK1 Hydroxymethylglutaryl-coenzyme A reductase. (519 aa)    
Predicted Functional Partners:
menA
1,4-dihydroxy-2-naphthoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
    
 
 0.880
SMB98126.1
Hypothetical protein; SPTR: A1ZHF7 Phospholipid/glycerol acyltransferase, putative; KEGG: acp:A2cp1_0453 phospholipid/glycerol acyltransferase.
  
 
 
 0.663
SMB91004.1
Monooxygenase FAD-binding; InterPro IPR003042:IPR002938; COGs: COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase; KEGG: mxa:MXAN_3398 FAD-dependent oxidoreductase; SPTR: A3YFX8 Putative uncharacterized protein; PFAM: monooxygenase FAD-binding.
   
  
 0.615
kmo
Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
   
  
 0.615
lipA
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
 
      0.546
SMB94242.1
Hypothetical protein.
       0.532
SMB82594.1
Polyprenyl synthetase; InterPro IPR000092; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; KEGG: gme:Gmet_2455 polyprenyl synthetase; SPTR: A1ZEX4 Geranylgeranyl pyrophosphate synthetase (Ggpp synthetase) (Ggps); PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
 
 0.487
SMB94259.1
Hypothetical protein.
       0.483
SMB93140.1
Nicotinamidase; InterPro IPR000868; COGs: COG1335 Amidase related to nicotinamidase; KEGG: lpn:lpg0271 bifunctional pyrazinamidase/nicotinamidase; SPTR: A3XR27 Bifunctional pyrazinamidase/nicotinamidase; PFAM: isochorismatase hydrolase; PRIAM: Nicotinamidase.
 
      0.471
SMB86459.1
CBS domain containing protein; InterPro IPR000644; KEGG: bsu:BSU29700 acetoin dehydrogenase; SPTR: A1ZP28 CBS domain pair protein; PFAM: CBS domain containing protein.
    
 0.468
Your Current Organism:
Hymenobacter roseosalivarius
NCBI taxonomy Id: 645990
Other names: H. roseosalivarius DSM 11622, Hymenobacter roseosalivarius AA-718, Hymenobacter roseosalivarius DSM 11622, Hymenobacter roseosalivarius str. DSM 11622, Hymenobacter roseosalivarius strain DSM 11622
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.