STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
SMB91898.1Two component transcriptional regulator, LuxR family; InterPro IPR000792:IPR001789; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; KEGG: hch:HCH_00419 response regulator; SPTR: A1ZYF0 DNA-binding response regulator, LuxR family; SMART: response regulator receiver; regulatory protein LuxR; PFAM: response regulator receiver; regulatory protein LuxR. (213 aa)    
Predicted Functional Partners:
SMB91900.1
PAS/PAC sensor signal transduction histidine kinase; InterPro IPR004358:IPR013655:IPR013767:IPR003594:IPR013656:IPR0016 10:IPR000014:IPR000700:IPR005467; COGs: COG4585 Signal transduction histidine kinase; KEGG: reh:H16_A1985 signal transduction histidine kinase containing PAS/PAC sensor domain; SPTR: A1ZEE5 Multi-sensor Hybrid Histidine Kinase, putative; SMART: ATP-binding region ATPase domain protein; PAC repeat-containing protein; PAS domain containing protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain prote [...]
 
 0.979
SMB98473.1
Multi-sensor hybrid histidine kinase; InterPro IPR004358:IPR003018:IPR013656:IPR013767:IPR003594:IPR0036 61:IPR008207:IPR001789:IPR001610:IPR000014:IPR000700:IPR0 05467; COGs: COG0642 Signal transduction histidine kinase; KEGG: gsu:GSU2314 sensory box histidine kinase/response regulator; SPTR: A1ZKB7 Sensor protein; SMART: response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; GAF domain protein; ATP-binding region ATPase domain protein; PAS domain containing protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; GA [...]
  
 0.973
SMB93608.1
Putative PAS/PAC sensor protein; InterPro IPR013656:IPR000014:IPR000700; KEGG: azo:azo1544 GGDEF/EAL/PAC/PAS-domain-containing protein; SPTR: A3J744 Sensor protein; SMART: PAS domain containing protein; PFAM: PAS fold-4 domain protein; TIGRFAM: PAS sensor protein.
   
 0.913
SMB98154.1
Multi-sensor hybrid histidine kinase; InterPro IPR004358:IPR013655:IPR001789:IPR013767:IPR013656:IPR0035 94:IPR003661:IPR001610:IPR000014:IPR008207:IPR000700:IPR0 05467; COGs: COG0642 Signal transduction histidine kinase; KEGG: tdn:Suden_0219 multi-sensor hybrid histidine kinase; SPTR: A3HWD5 Sensor protein; SMART: response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; ATP-binding region ATPase domain protein; PFAM: response regulator receiver; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain pr [...]
  
 0.913
SMB79968.1
PAS/PAC sensor hybrid histidine kinase; InterPro IPR004358:IPR013655:IPR001789:IPR013656:IPR013767:IPR0035 94:IPR003661:IPR001610:IPR000014:IPR000700:IPR005467; COGs: COG0642 Signal transduction histidine kinase; KEGG: cak:Caul_0720 multi-sensor hybrid histidine kinase; SPTR: A4BZQ5 Sensor protein; SMART: response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; ATP-binding region ATPase domain protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; PAS fold-4 do [...]
  
 0.913
SMB98618.1
PAS/PAC sensor signal transduction histidine kinase; InterPro IPR004358:IPR013767:IPR003594:IPR013656:IPR001610:IPR0000 14:IPR000700:IPR005467; COGs: COG4585 Signal transduction histidine kinase; KEGG: sfu:Sfum_3668 PAS/PAC sensor signal transduction histidine kinase; SPTR: A1ZEE5 Multi-sensor Hybrid Histidine Kinase, putative; SMART: ATP-binding region ATPase domain protein; PAC repeat-containing protein; PAS domain containing protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; PRIAM: Histidine kinase; TIGRFAM: PAS sensor protein.
 0.905
SMB99696.1
PAS/PAC sensor signal transduction histidine kinase; InterPro IPR004358:IPR013655:IPR013767:IPR013656:IPR003594:IPR0016 10:IPR000700:IPR005467:IPR000014; COGs: COG4585 Signal transduction histidine kinase; KEGG: sus:Acid_2792 PAS/PAC sensor signal transduction histidine kinase; SPTR: A3XHI9 Sensory box histidine kinase; SMART: PAC repeat-containing protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; PAS fold-3 domain protein; PAS fold domain protein; PRIAM: Histidine kinase; TIGRFAM: PAS sensor protein.
 
  0.868
SMB90378.1
Histidine kinase; InterPro IPR004358:IPR011712:IPR003594:IPR005467; COGs: COG4585 Signal transduction histidine kinase; KEGG: rme:Rmet_3575 periplasmic sensor signal transduction histidine kinase; SPTR: A1ZJR9 Sensor protein ComP, putative; SMART: ATP-binding region ATPase domain protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; PRIAM: Histidine kinase.
 
  0.868
SMC00669.1
Putative sensor with HAMP domain; InterPro IPR003660; KEGG: bja:bll2599 two-component hybrid sensor and regulator; SPTR: A1YBU7 Sensor protein (Fragment); SMART: histidine kinase HAMP region domain protein; PFAM: histidine kinase HAMP region domain protein.
   
 0.856
SMB95744.1
Transcriptional regulator, LytTR family; InterPro IPR007492:IPR003018; COGs: COG3279 Response regulator of the LytR/AlgR family; KEGG: amc:MADE_03205 histidine kinase response regulator hybrid protein; SPTR: A0ZB66 Sensor protein; SMART: GAF domain protein; PFAM: LytTr DNA-binding region; GAF domain protein.
  
 0.788
Your Current Organism:
Hymenobacter roseosalivarius
NCBI taxonomy Id: 645990
Other names: H. roseosalivarius DSM 11622, Hymenobacter roseosalivarius AA-718, Hymenobacter roseosalivarius DSM 11622, Hymenobacter roseosalivarius str. DSM 11622, Hymenobacter roseosalivarius strain DSM 11622
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