STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB96656.1KEGG: dol:Dole_0855 sodium/hydrogen exchanger; SPTR: Q0W0D3 Putative Na(+)/H(+) antiporter; PFAM: sodium/hydrogen exchanger; TrkA-N domain protein; TrkA-C domain protein; InterPro IPR006037:IPR003148:IPR006153; COGs: COG0475 Kef-type K+ transport systems membrane components; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (597 aa)    
Predicted Functional Partners:
SMB96654.1
KEGG: dvl:Dvul_0955 sodium/hydrogen exchanger; SPTR: A0B8M5 Sodium/hydrogen exchanger.
 
   
 0.971
SMB97057.1
InterPro IPR001607; KEGG: sus:Acid_1708 hypothetical protein; SPTR: A2W5E5 Isopeptidase T.
    
 0.917
SMB92891.1
Kef-type potassium/proton antiporter, CPA2 family (TC 2.A.37.1); InterPro IPR003148:IPR006153:IPR004771; COGs: COG0475 Kef-type K+ transport systems membrane components; KEGG: ppd:Ppro_2060 potassium efflux system protein; SPTR: A3HTD3 Potassium efflux system protein; PFAM: sodium/hydrogen exchanger; TrkA-N domain protein; TIGRFAM: potassium efflux system protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
 
   
0.639
SMC00254.1
Competence/damage-inducible protein cinA; InterPro IPR001453:IPR008136:IPR008135; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; KEGG: dal:Dalk_4012 competence/damage-inducible protein CinA; SPTR: A1ZUS5 Competence-damage inducible protein; PFAM: CinA domain protein; molybdopterin binding domain; TIGRFAM: competence/damage-inducible protein CinA.
    
 0.592
SMB84816.1
Molybdopterin biosynthesis MoaE protein; InterPro IPR003448; COGs: COG0314 Molybdopterin converting factor large subunit; KEGG: bha:BH3019 molybdopterin converting factor (subunit 2); SPTR: A1ZKS9 Molybdopterin converting factor, subunit 2; PFAM: molybdopterin biosynthesis MoaE protein.
   
    0.563
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
  0.547
SMB85663.1
InterPro IPR003754; COGs: COG1587 Uroporphyrinogen-III synthase; KEGG: similar to uroporphyrinogen III synthase; K01719 uroporphyrinogen-III synthase; SPTR: A1ZTV5 Uroporphyrinogen-III synthase; PFAM: Uroporphyrinogen III synthase HEM4.
  
    0.523
ruvB
Holliday junction DNA helicase subunit RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
  
    0.489
SMB98402.1
UspA domain protein; InterPro IPR006015:IPR006016; COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; KEGG: dol:Dole_2256 UspA domain-containing protein; SPTR: A3XHU0 Universal stress protein; PFAM: UspA domain protein.
 
  
 0.434
SMB99323.1
Two component transcriptional regulator, AraC family; InterProIPR000005:IPR004358:IPR001761:IPR001789:IPR 003594:IPR003661:IPR005467; COGs: COG1879 ABC-type sugar transport system periplasmic component; KEGG: pat:Patl_1836 two component AraC family transcriptional regulator; SPTR: A5ZIK5 Sensor protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; helix-turn-helix- domain containing protein AraC type; histidine kinase A domain protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; periplasmic binding protein/LacI transcrip [...]
 
  
 0.415
Your Current Organism:
Hymenobacter roseosalivarius
NCBI taxonomy Id: 645990
Other names: H. roseosalivarius DSM 11622, Hymenobacter roseosalivarius AA-718, Hymenobacter roseosalivarius DSM 11622, Hymenobacter roseosalivarius str. DSM 11622, Hymenobacter roseosalivarius strain DSM 11622
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