STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB98473.1Multi-sensor hybrid histidine kinase; InterPro IPR004358:IPR003018:IPR013656:IPR013767:IPR003594:IPR0036 61:IPR008207:IPR001789:IPR001610:IPR000014:IPR000700:IPR0 05467; COGs: COG0642 Signal transduction histidine kinase; KEGG: gsu:GSU2314 sensory box histidine kinase/response regulator; SPTR: A1ZKB7 Sensor protein; SMART: response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; GAF domain protein; ATP-binding region ATPase domain protein; PAS domain containing protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; GA [...] (1350 aa)    
Predicted Functional Partners:
SMB99251.1
PAS/PAC sensor signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR013767:IPR013656:IPR 003594:IPR003661:IPR001610:IPR000014:IPR000700:IPR005467; COGs: COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase); KEGG: scl:sce5100 two-component hybrid histidine kinase; SPTR: A1ZIZ7 Sensor protein; SMART: ATP-binding region ATPase domain protein; PAC repeat-containing protein; histidine kinase A domain protein; PAS domain containing protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; PAS fold domain protein; PAS fol [...]
 
0.999
SMB99323.1
Two component transcriptional regulator, AraC family; InterProIPR000005:IPR004358:IPR001761:IPR001789:IPR 003594:IPR003661:IPR005467; COGs: COG1879 ABC-type sugar transport system periplasmic component; KEGG: pat:Patl_1836 two component AraC family transcriptional regulator; SPTR: A5ZIK5 Sensor protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; helix-turn-helix- domain containing protein AraC type; histidine kinase A domain protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; periplasmic binding protein/LacI transcrip [...]
 
0.999
SMB97324.1
KEGG: mgm:Mmc1_1088 hypothetical protein.
  
 0.999
SMB95682.1
PAS/PAC sensor signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR013767:IPR003594:IPR 013656:IPR003661:IPR001610:IPR000014:IPR000700:IPR005467; COGs: COG0642 Signal transduction histidine kinase; KEGG: scl:sce5100 two-component hybrid histidine kinase; SPTR: A0YNE5 Sensor protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A [...]
 
0.999
SMB95744.1
Transcriptional regulator, LytTR family; InterPro IPR007492:IPR003018; COGs: COG3279 Response regulator of the LytR/AlgR family; KEGG: amc:MADE_03205 histidine kinase response regulator hybrid protein; SPTR: A0ZB66 Sensor protein; SMART: GAF domain protein; PFAM: LytTr DNA-binding region; GAF domain protein.
 
 0.999
SMB91065.1
Two component transcriptional regulator, winged helix family; InterPro IPR001789:IPR001867; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; SPTR: A2TSA3 Two-component system, transcriptional regulatory protein; SMART: response regulator receiver; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: gur:Gura_1334 two component transcriptional regulator.
 
 0.999
SMB98325.1
InterPro IPR001789; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; KEGG: met:M446_0185 response regulator receiver protein; SPTR: A3HV32 Two-component response regulator; SMART: response regulator receiver; PFAM: response regulator receiver.
 
 0.999
SMB98422.1
KEGG: mgm:Mmc1_3175 phage shock protein A, PspA; SPTR: A3XLX1 Putative uncharacterized protein; PFAM: PspA/IM30 family protein; COGs: COG1842 Phage shock protein A (IM30) suppresses sigma54-dependent transcription; InterPro IPR007157:IPR006162.
    
 
 0.999
SMB88042.1
PAS/PAC sensor signal transduction histidine kinase; InterPro IPR004358:IPR003594:IPR013656:IPR003661:IPR005467; COGs: COG0642 Signal transduction histidine kinase; KEGG: scl:sce0206 two-component system sensor histidine kinase/response regulator, hybrid ('one-component system'); SPTR: A1ZIZ7 Sensor protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; histidine kinase A domain protein.
 
0.999
SMB88111.1
InterPro IPR001789; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; KEGG: met:M446_5294 response regulator receiver protein; SPTR: A3HV32 Two-component response regulator; SMART: response regulator receiver; PFAM: response regulator receiver.
 
 0.999
Your Current Organism:
Hymenobacter roseosalivarius
NCBI taxonomy Id: 645990
Other names: H. roseosalivarius DSM 11622, Hymenobacter roseosalivarius AA-718, Hymenobacter roseosalivarius DSM 11622, Hymenobacter roseosalivarius str. DSM 11622, Hymenobacter roseosalivarius strain DSM 11622
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.