STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB98566.1DNA-(apurinic or apyrimidinic site) lyase; PRIAM: DNA-formamidopyrimidine glycosylase; InterPro IPR012319:IPR015886; COGs: COG0266 Formamidopyrimidine-DNA glycosylase; KEGG: ATFPG-1/ATFPG-2/ATMMH-1/ATMMH-2/FPG-1/FPG-2 (FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE 1, FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE 2); DNA N-glycosylase; K10563 formamidopyrimidine-DNA glycosylase; SPTR: A1ZMR0 DNA glycosylase; PFAM: Formamidopyrimidine-DNA glycosylase catalytic domain protein; DNA glycosylase/AP lyase, H2TH DNA-binding. (271 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.988
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
 
  
 0.816
SMB99930.1
DNA polymerase III, epsilon subunit; InterPro IPR000305:IPR013520:IPR006055:IPR006054; COGs: COG2176 DNA polymerase III alpha subunit (gram-positive type); KEGG: dar:Daro_1907 DNA polymerase III, epsilon subunit; SPTR: A1ZC44 DNA polymerase III, epsilon subunit; SMART: Exonuclease; Excinuclease ABC C subunit domain protein; PFAM: Exonuclease RNase T and DNA polymerase III; Excinuclease ABC C subunit domain protein; PRIAM: DNA-directed DNA polymerase; TIGRFAM: DNA polymerase III, epsilon subunit.
  
 
 0.681
SMB87820.1
KEGG: smt:Smal_0900 hypothetical protein; SPTR: Q9ZX97 Gp52.
  
  
 0.621
uvrC
Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
   
 
 0.546
SMB98567.1
Phenazine biosynthesis protein PhzF family; InterPro IPR003719; COGs: COG0384 epimerase PhzC/PhzF homolog; KEGG: sil:SPO0897 PhzF family phenazine biosynthesis protein; SPTR: A3W5C6 Phenazine biosynthesis protein, PhzF family protein; PFAM: Phenazine biosynthesis PhzC/PhzF protein; TIGRFAM: phenazine biosynthesis protein PhzF family.
       0.493
nth
DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
   
  
 0.451
SMB98759.1
InterPro IPR014127; KEGG: sfu:Sfum_0347 hypothetical protein; SPTR: A3I304 Putative uncharacterized protein.
   
  
 0.451
SMB96875.1
HhH-GPD family protein; InterPro IPR003265; COGs: COG0177 EndoIII-related endonuclease; KEGG: met:M446_3412 helix-hairpin-helix DNA-binding motif-containing protein; SPTR: A0B7M5 HhH-GPD family protein; SMART: HhH-GPD family protein; PFAM: HhH-GPD family protein.
   
  
 0.451
SMB88664.1
HhH-GPD family protein; InterPro IPR003265; COGs: COG0177 EndoIII-related endonuclease; KEGG: met:M446_3412 helix-hairpin-helix DNA-binding motif-containing protein; SPTR: A5P905 Endonuclease III family protein; SMART: HhH-GPD family protein; PFAM: HhH-GPD family protein.
   
  
 0.451
Your Current Organism:
Hymenobacter roseosalivarius
NCBI taxonomy Id: 645990
Other names: H. roseosalivarius DSM 11622, Hymenobacter roseosalivarius AA-718, Hymenobacter roseosalivarius DSM 11622, Hymenobacter roseosalivarius str. DSM 11622, Hymenobacter roseosalivarius strain DSM 11622
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