node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SMB84748.1 | SMB84814.1 | SAMN00120144_3852 | SAMN00120144_3859 | KEGG: sus:Acid_2933 hypothetical protein; SPTR: A4AN50 Putative uncharacterized protein. | thiamineS protein; InterPro IPR003749; KEGG: CNX7/SIR5; catalytic; SPTR: A4BX00 Putative molybdopterin-synthase small subunit; PFAM: thiamineS protein. | 0.481 |
SMB84748.1 | fdhD | SAMN00120144_3852 | SAMN00120144_3853 | KEGG: sus:Acid_2933 hypothetical protein; SPTR: A4AN50 Putative uncharacterized protein. | Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. | 0.662 |
SMB84748.1 | mobA | SAMN00120144_3852 | SAMN00120144_3861 | KEGG: sus:Acid_2933 hypothetical protein; SPTR: A4AN50 Putative uncharacterized protein. | Molybdopterin-guanine dinucleotide biosynthesis protein A-like; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. | 0.609 |
SMB84771.1 | SMB84802.1 | SAMN00120144_3854 | SAMN00120144_3858 | UBA/THIF-type NAD/FAD binding protein; InterPro IPR007901:IPR000594:IPR001763:IPR001307; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; KEGG: cbc:CbuK_0743 molybdopterin biosynthesis MoeB protein; SPTR: A1ZVV1 Molybdopterin biosynthesis protein; SMART: Rhodanese domain protein; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein. | Cyclic pyranopterin monophosphate synthase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.709 |
SMB84771.1 | SMB84814.1 | SAMN00120144_3854 | SAMN00120144_3859 | UBA/THIF-type NAD/FAD binding protein; InterPro IPR007901:IPR000594:IPR001763:IPR001307; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; KEGG: cbc:CbuK_0743 molybdopterin biosynthesis MoeB protein; SPTR: A1ZVV1 Molybdopterin biosynthesis protein; SMART: Rhodanese domain protein; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein. | thiamineS protein; InterPro IPR003749; KEGG: CNX7/SIR5; catalytic; SPTR: A4BX00 Putative molybdopterin-synthase small subunit; PFAM: thiamineS protein. | 0.981 |
SMB84771.1 | SMB84816.1 | SAMN00120144_3854 | SAMN00120144_3860 | UBA/THIF-type NAD/FAD binding protein; InterPro IPR007901:IPR000594:IPR001763:IPR001307; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; KEGG: cbc:CbuK_0743 molybdopterin biosynthesis MoeB protein; SPTR: A1ZVV1 Molybdopterin biosynthesis protein; SMART: Rhodanese domain protein; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein. | Molybdopterin biosynthesis MoaE protein; InterPro IPR003448; COGs: COG0314 Molybdopterin converting factor large subunit; KEGG: bha:BH3019 molybdopterin converting factor (subunit 2); SPTR: A1ZKS9 Molybdopterin converting factor, subunit 2; PFAM: molybdopterin biosynthesis MoaE protein. | 0.997 |
SMB84771.1 | SMB84830.1 | SAMN00120144_3854 | SAMN00120144_3862 | UBA/THIF-type NAD/FAD binding protein; InterPro IPR007901:IPR000594:IPR001763:IPR001307; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; KEGG: cbc:CbuK_0743 molybdopterin biosynthesis MoeB protein; SPTR: A1ZVV1 Molybdopterin biosynthesis protein; SMART: Rhodanese domain protein; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein. | Cyclic pyranopterin monophosphate synthase subunit MoaC; InterPro IPR002820; COGs: COG0315 Molybdenum cofactor biosynthesis enzyme; KEGG: xoo:XOO1061 molybdenum cofactor biosynthesis protein C; SPTR: A1ZUU4 Molybdenum cofactor biosynthesis protein C; PFAM: molybdopterin cofactor biosynthesis MoaC region; TIGRFAM: molybdenum cofactor biosynthesis protein C. | 0.674 |
SMB84771.1 | SMB84836.1 | SAMN00120144_3854 | SAMN00120144_3863 | UBA/THIF-type NAD/FAD binding protein; InterPro IPR007901:IPR000594:IPR001763:IPR001307; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; KEGG: cbc:CbuK_0743 molybdopterin biosynthesis MoeB protein; SPTR: A1ZVV1 Molybdopterin biosynthesis protein; SMART: Rhodanese domain protein; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein. | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.781 |
SMB84771.1 | fdhD | SAMN00120144_3854 | SAMN00120144_3853 | UBA/THIF-type NAD/FAD binding protein; InterPro IPR007901:IPR000594:IPR001763:IPR001307; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; KEGG: cbc:CbuK_0743 molybdopterin biosynthesis MoeB protein; SPTR: A1ZVV1 Molybdopterin biosynthesis protein; SMART: Rhodanese domain protein; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein. | Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. | 0.810 |
SMB84771.1 | hisI | SAMN00120144_3854 | SAMN00120144_2772 | UBA/THIF-type NAD/FAD binding protein; InterPro IPR007901:IPR000594:IPR001763:IPR001307; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; KEGG: cbc:CbuK_0743 molybdopterin biosynthesis MoeB protein; SPTR: A1ZVV1 Molybdopterin biosynthesis protein; SMART: Rhodanese domain protein; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein. | InterPro IPR002496:IPR008179; COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; KEGG: amc:MADE_01111 phosphoribosyl-ATP pyrophosphatase/phosphoribosyl-AMP cyclohydrolase; SPTR: A3HZJ3 Phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; TIGRFAM: phosphoribosyl-ATP diphosphatase; In the N-terminal section; belongs to the PRA-CH family. | 0.595 |
SMB84771.1 | mobA | SAMN00120144_3854 | SAMN00120144_3861 | UBA/THIF-type NAD/FAD binding protein; InterPro IPR007901:IPR000594:IPR001763:IPR001307; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; KEGG: cbc:CbuK_0743 molybdopterin biosynthesis MoeB protein; SPTR: A1ZVV1 Molybdopterin biosynthesis protein; SMART: Rhodanese domain protein; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein. | Molybdopterin-guanine dinucleotide biosynthesis protein A-like; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. | 0.645 |
SMB84802.1 | SMB84771.1 | SAMN00120144_3858 | SAMN00120144_3854 | Cyclic pyranopterin monophosphate synthase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | UBA/THIF-type NAD/FAD binding protein; InterPro IPR007901:IPR000594:IPR001763:IPR001307; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; KEGG: cbc:CbuK_0743 molybdopterin biosynthesis MoeB protein; SPTR: A1ZVV1 Molybdopterin biosynthesis protein; SMART: Rhodanese domain protein; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein. | 0.709 |
SMB84802.1 | SMB84814.1 | SAMN00120144_3858 | SAMN00120144_3859 | Cyclic pyranopterin monophosphate synthase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | thiamineS protein; InterPro IPR003749; KEGG: CNX7/SIR5; catalytic; SPTR: A4BX00 Putative molybdopterin-synthase small subunit; PFAM: thiamineS protein. | 0.961 |
SMB84802.1 | SMB84816.1 | SAMN00120144_3858 | SAMN00120144_3860 | Cyclic pyranopterin monophosphate synthase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Molybdopterin biosynthesis MoaE protein; InterPro IPR003448; COGs: COG0314 Molybdopterin converting factor large subunit; KEGG: bha:BH3019 molybdopterin converting factor (subunit 2); SPTR: A1ZKS9 Molybdopterin converting factor, subunit 2; PFAM: molybdopterin biosynthesis MoaE protein. | 0.954 |
SMB84802.1 | SMB84830.1 | SAMN00120144_3858 | SAMN00120144_3862 | Cyclic pyranopterin monophosphate synthase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Cyclic pyranopterin monophosphate synthase subunit MoaC; InterPro IPR002820; COGs: COG0315 Molybdenum cofactor biosynthesis enzyme; KEGG: xoo:XOO1061 molybdenum cofactor biosynthesis protein C; SPTR: A1ZUU4 Molybdenum cofactor biosynthesis protein C; PFAM: molybdopterin cofactor biosynthesis MoaC region; TIGRFAM: molybdenum cofactor biosynthesis protein C. | 0.999 |
SMB84802.1 | SMB84836.1 | SAMN00120144_3858 | SAMN00120144_3863 | Cyclic pyranopterin monophosphate synthase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.904 |
SMB84802.1 | fdhD | SAMN00120144_3858 | SAMN00120144_3853 | Cyclic pyranopterin monophosphate synthase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. | 0.804 |
SMB84802.1 | mobA | SAMN00120144_3858 | SAMN00120144_3861 | Cyclic pyranopterin monophosphate synthase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Molybdopterin-guanine dinucleotide biosynthesis protein A-like; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. | 0.853 |
SMB84814.1 | SMB84748.1 | SAMN00120144_3859 | SAMN00120144_3852 | thiamineS protein; InterPro IPR003749; KEGG: CNX7/SIR5; catalytic; SPTR: A4BX00 Putative molybdopterin-synthase small subunit; PFAM: thiamineS protein. | KEGG: sus:Acid_2933 hypothetical protein; SPTR: A4AN50 Putative uncharacterized protein. | 0.481 |
SMB84814.1 | SMB84771.1 | SAMN00120144_3859 | SAMN00120144_3854 | thiamineS protein; InterPro IPR003749; KEGG: CNX7/SIR5; catalytic; SPTR: A4BX00 Putative molybdopterin-synthase small subunit; PFAM: thiamineS protein. | UBA/THIF-type NAD/FAD binding protein; InterPro IPR007901:IPR000594:IPR001763:IPR001307; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; KEGG: cbc:CbuK_0743 molybdopterin biosynthesis MoeB protein; SPTR: A1ZVV1 Molybdopterin biosynthesis protein; SMART: Rhodanese domain protein; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein. | 0.981 |