STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (160 aa)    
Predicted Functional Partners:
coaX
Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
 
  
 0.902
SMB89841.1
Phosphopantothenate--cysteine ligase; InterPro IPR007085; COGs: COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; KEGG: dps:DP1673 DNA/pantothenate metabolism flavoprotein; SPTR: A4CLV1 Flavoprotein; PFAM: DNA/pantothenate metabolism flavoprotein domain protein; PRIAM: Phosphopantothenate--cysteine ligase.
 
  
 0.896
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
 
  
 0.894
SMB89832.1
Phosphopantothenate--cysteine ligase; InterPro IPR003382; COGs: COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; KEGG: afr:AFE_0357 phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; SPTR: A3HXA5 Flavoprotein; PFAM: flavoprotein; PRIAM: Phosphopantothenate--cysteine ligase.
 
  
 0.886
SMB99099.1
Protein of unknown function DUF479; InterPro IPR007431; COGs: COG3124 conserved hypothetical protein; KEGG: pst:PSPTO_4355 hypothetical protein; SPTR: A4BPE7 Putative uncharacterized protein; PFAM: protein of unknown function DUF479.
     
 0.844
SMB97569.1
Riboflavin biosynthesis protein RibF; InterPro IPR015864:IPR015865:IPR002606; COGs: COG0196 FAD synthase; KEGG: mca:MCA2252 riboflavin biosynthesis protein RibF; SPTR: A3HSS6 Riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin biosynthesis protein RibF; Belongs to the ribF family.
 
   
 0.791
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
 
   
 0.731
SMB98074.1
Hypothetical protein; SPTR: A1ZTS4 Putative uncharacterized protein.
       0.685
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.664
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
   
 0.631
Your Current Organism:
Hymenobacter roseosalivarius
NCBI taxonomy Id: 645990
Other names: H. roseosalivarius DSM 11622, Hymenobacter roseosalivarius AA-718, Hymenobacter roseosalivarius DSM 11622, Hymenobacter roseosalivarius str. DSM 11622, Hymenobacter roseosalivarius strain DSM 11622
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.