STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
SMB81651.1Putative GAF sensor protein; InterPro IPR003018; COGs: COG1956 GAF domain-containing protein; KEGG: gafA; GAF domain-containing protein; SPTR: A1ZKI5 GAF domain-containing protein, involved in signal transduction; SMART: GAF domain protein; PFAM: GAF domain protein. (160 aa)    
Predicted Functional Partners:
SMB96882.1
Transferase hexapeptide repeat family protein; InterPro IPR001451; COGs: COG0663 Carbonic anhydrase/acetyltransferase isoleucine patch superfamily; KEGG: mxa:MXAN_3783 transferase hexapeptide repeat family protein; SPTR: A3I089 Hexapeptide transferase family protein.
      0.677
SMB81640.1
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
       0.603
SMC00669.1
Putative sensor with HAMP domain; InterPro IPR003660; KEGG: bja:bll2599 two-component hybrid sensor and regulator; SPTR: A1YBU7 Sensor protein (Fragment); SMART: histidine kinase HAMP region domain protein; PFAM: histidine kinase HAMP region domain protein.
    
  0.531
SMB98324.1
Adenylate/guanylate cyclase; InterPro IPR001054:IPR001789; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); KEGG: scl:sce8885 protein kinase; SPTR: A3HV31 Two-component response regulator; SMART: response regulator receiver; adenylyl cyclase class-3/4/guanylyl cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; response regulator receiver.
    
  0.487
SMB88104.1
Adenylate/guanylate cyclase; InterPro IPR001054:IPR001789; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); KEGG: scl:sce5834 protein kinase; SPTR: A3HV31 Two-component response regulator; SMART: response regulator receiver; adenylyl cyclase class-3/4/guanylyl cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; response regulator receiver.
    
  0.487
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
    
 0.472
SMB81630.1
Modification methylase, HemK family; InterPro IPR007848:IPR002052:IPR004556; COGs: COG2890 Methylase of polypeptide chain release factors; KEGG: gbm:Gbem_3708 protein-(glutamine-N5) methyltransferase, release factor-specific; SPTR: A1ZCC3 Protoporphyrinogen oxidase; TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small.
       0.422
Your Current Organism:
Hymenobacter roseosalivarius
NCBI taxonomy Id: 645990
Other names: H. roseosalivarius DSM 11622, Hymenobacter roseosalivarius AA-718, Hymenobacter roseosalivarius DSM 11622, Hymenobacter roseosalivarius str. DSM 11622, Hymenobacter roseosalivarius strain DSM 11622
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.