STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sgly_0182phenylacetate-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). (431 aa)    
Predicted Functional Partners:
Sgly_1633
Phenylacetic acid degradation-related protein; COGs: COG2050 Uncharacterized protein possibly involved in aromatic compounds catabolism; InterPro IPR003736: IPR006683; KEGG: mma:MM_1896 phenylacetic acid degradation protein; PFAM: Thioesterase superfamily; SPTR: Phenylacetic acid degradation protein; TIGRFAM: Phenylacetic acid degradation-related protein; PFAM: Thioesterase superfamily; TIGRFAM: uncharacterized domain 1; phenylacetic acid degradation protein PaaD.
 
 
 0.969
Sgly_3082
phenylacetate-CoA ligase; COGs: COG1541 Coenzyme F390 synthetase; InterPro IPR000873; KEGG: cce:Ccel_1392 coenzyme F390 synthetase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Phenylacetate--CoA ligase; SPTR: Phenylacetate--CoA ligase; PFAM: AMP-binding enzyme.
  
  
 
0.908
Sgly_0696
phenylacetate-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).
  
  
 
0.904
Sgly_0697
COGs: COG4747 ACT domain-containing protein; InterPro IPR002912; KEGG: aar:Acear_1789 ACT domain protein; PFAM: Amino acid-binding ACT; SPTR: ACT domain protein; PFAM: ACT domain.
 
   0.776
Sgly_2728
COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR001670; KEGG: afl:Aflv_2814 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, iron-type; PRIAM: Acetaldehyde dehydrogenase (acetylating); SPTR: Iron-containing alcohol dehydrogenase; PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.655
Sgly_1138
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: cbb:CLD_3461 aldehyde dehydrogenase family protein; PFAM: Aldehyde dehydrogenase; SPTR: Aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family.
  
 
 0.596
Sgly_0181
Indolepyruvate ferredoxin oxidoreductase, alpha subunit; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
    0.573
Sgly_0180
COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR019752; KEGG: cth:Cthe_0614 indolepyruvate oxidoreductase subunit beta; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; PRIAM: Indolepyruvate ferredoxin oxidoreductase; SPTR: Putative uncharacterized protein; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: indolepyruvate ferredoxin oxidoreductase, beta subunit.
 
    0.564
Sgly_0179
Radical SAM domain protein; COGs: COG4277 DNA-binding protein with the Helix-hairpin-helix motif; InterPro IPR007197; KEGG: hmo:HM1_1854 radical sam domain protein, putative; PFAM: Radical SAM; SPTR: Radical sam domain protein, putative.
       0.465
Sgly_0183
Prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
       0.426
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.