STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sgly_0259Transcriptional regulator, TetR family; COGs: COG1309 Transcriptional regulator; InterPro IPR001647; KEGG: dsy:DSY2813 hypothetical protein; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Putative uncharacterized protein; PFAM: Bacterial regulatory proteins, tetR family. (201 aa)    
Predicted Functional Partners:
Sgly_0260
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661: IPR003594; KEGG: tjr:TherJR_2639 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
       0.636
Sgly_0261
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: tjr:TherJR_2638 two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcripti [...]
       0.636
Sgly_0258
KEGG: dhd:Dhaf_3957 hypothetical protein; SPTR: Uncharacterized Zn-finger protein.
       0.595
Sgly_2590
Regulatory protein TetR; InterPro IPR001647; KEGG: amt:Amet_0189 TetR family transcriptional regulator; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family.
  
     0.432
Sgly_0280
Transcriptional regulator, TetR family; COGs: COG1309 Transcriptional regulator; InterPro IPR001647; KEGG: ols:Olsu_0226 transcriptional regulator, TetR family; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family.
  
     0.407
Sgly_0262
Penicillin-binding protein, 1A family; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR001264: IPR001460: IPR011816; KEGG: dhd:Dhaf_0235 penicillin-binding protein, 1A family; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; SPTR: Putative uncharacterized protein; TIGRFAM: Penicillin-binding protein 1A; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family.
       0.404
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.