STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sgly_0324KEGG: spj:MGAS2096_Spy0566 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated. (210 aa)    
Predicted Functional Partners:
Sgly_0318
KEGG: mag:amb1515 hypothetical protein; SPTR: Putative uncharacterized protein.
  
    0.925
Sgly_2095
Helicase c2; COGs: COG1199 Rad3-related DNA helicase; InterPro IPR014001: IPR006554: IPR006555; KEGG: dhd:Dhaf_3029 DnaQ family exonuclease/DinG family helicase; SMART: Helicase, ATP-dependent, c2 type; DEAD-like helicase, N-terminal; Helicase-like, DEXD box c2 type; SPTR: Putative uncharacterized protein; PFAM: DEAD_2; DEAD/DEAH box helicase; TIGRFAM: DnaQ family exonuclease/DinG family helicase, putative.
   
 0.869
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  0.838
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.832
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
  0.831
Sgly_0291
NUDIX hydrolase; COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR000086; KEGG: dsy:DSY0429 hypothetical protein; PFAM: NUDIX hydrolase domain; SPTR: Putative uncharacterized protein; PFAM: NUDIX domain.
   
 0.830
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.800
Sgly_0322
KEGG: cce:Ccel_3308 phage protein; SPTR: Phage protein.
       0.784
Sgly_0325
Primase 2; COGs: COG3598 RecA-family ATPase; InterPro IPR014819; KEGG: cce:Ccel_3304 primase 2; PFAM: Primase, C-terminal 2; SPTR: Primase 2; PFAM: Primase C terminal 2 (PriCT-2).
       0.784
Sgly_0323
Type III restriction protein res subunit; COGs: COG1061 DNA or RNA helicase of superfamily II; InterPro IPR006935: IPR001650: IPR014001; KEGG: cce:Ccel_3307 type III restriction protein res subunit; PFAM: Restriction endonuclease, type I, R subunit/Type III, Res subunit; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: Type III restriction protein res subunit; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit.
       0.779
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
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