node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sgly_3210 | Sgly_3367 | Sgly_3210 | Sgly_3367 | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Membrane protein insertase, YidC/Oxa1 family; COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708: IPR020001; KEGG: dhd:Dhaf_4959 60 kDa inner membrane insertion protein; PFAM: Membrane insertion protein, OxaA/YidC; SPTR: Putative uncharacterized protein; TIGRFAM: Membrane insertion protein, OxaA/YidC, core; PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain. | 0.975 |
Sgly_3210 | ffh | Sgly_3210 | Sgly_2306 | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.976 |
Sgly_3210 | ftsY | Sgly_3210 | Sgly_2310 | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.981 |
Sgly_3210 | nusG | Sgly_3210 | Sgly_0379 | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Transcription antitermination protein nusG; Participates in transcription elongation, termination and antitermination. | 0.472 |
Sgly_3210 | rplA | Sgly_3210 | Sgly_0381 | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | LSU ribosomal protein L1P; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.758 |
Sgly_3210 | rplK | Sgly_3210 | Sgly_0380 | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.760 |
Sgly_3210 | rpmG | Sgly_3210 | Sgly_0377 | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | HAMAP: Ribosomal protein L33; InterPro IPR001705; KEGG: dhd:Dhaf_0403 50S ribosomal protein L33; PFAM: Ribosomal protein L33; SPTR: 50S ribosomal protein L33; TIGRFAM: Ribosomal protein L33; PFAM: Ribosomal protein L33; TIGRFAM: ribosomal protein L33, bacterial type; Belongs to the bacterial ribosomal protein bL33 family. | 0.784 |
Sgly_3210 | secA | Sgly_3210 | Sgly_3257 | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.986 |
Sgly_3210 | secE | Sgly_3210 | Sgly_0378 | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.996 |
Sgly_3210 | secY | Sgly_3210 | Sgly_0411 | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.990 |
Sgly_3367 | Sgly_3210 | Sgly_3367 | Sgly_3210 | Membrane protein insertase, YidC/Oxa1 family; COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708: IPR020001; KEGG: dhd:Dhaf_4959 60 kDa inner membrane insertion protein; PFAM: Membrane insertion protein, OxaA/YidC; SPTR: Putative uncharacterized protein; TIGRFAM: Membrane insertion protein, OxaA/YidC, core; PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain. | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.975 |
Sgly_3367 | ffh | Sgly_3367 | Sgly_2306 | Membrane protein insertase, YidC/Oxa1 family; COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708: IPR020001; KEGG: dhd:Dhaf_4959 60 kDa inner membrane insertion protein; PFAM: Membrane insertion protein, OxaA/YidC; SPTR: Putative uncharacterized protein; TIGRFAM: Membrane insertion protein, OxaA/YidC, core; PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain. | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.949 |
Sgly_3367 | ftsY | Sgly_3367 | Sgly_2310 | Membrane protein insertase, YidC/Oxa1 family; COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708: IPR020001; KEGG: dhd:Dhaf_4959 60 kDa inner membrane insertion protein; PFAM: Membrane insertion protein, OxaA/YidC; SPTR: Putative uncharacterized protein; TIGRFAM: Membrane insertion protein, OxaA/YidC, core; PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.938 |
Sgly_3367 | rplA | Sgly_3367 | Sgly_0381 | Membrane protein insertase, YidC/Oxa1 family; COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708: IPR020001; KEGG: dhd:Dhaf_4959 60 kDa inner membrane insertion protein; PFAM: Membrane insertion protein, OxaA/YidC; SPTR: Putative uncharacterized protein; TIGRFAM: Membrane insertion protein, OxaA/YidC, core; PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain. | LSU ribosomal protein L1P; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.477 |
Sgly_3367 | rplK | Sgly_3367 | Sgly_0380 | Membrane protein insertase, YidC/Oxa1 family; COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708: IPR020001; KEGG: dhd:Dhaf_4959 60 kDa inner membrane insertion protein; PFAM: Membrane insertion protein, OxaA/YidC; SPTR: Putative uncharacterized protein; TIGRFAM: Membrane insertion protein, OxaA/YidC, core; PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain. | LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.506 |
Sgly_3367 | rpmG | Sgly_3367 | Sgly_0377 | Membrane protein insertase, YidC/Oxa1 family; COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708: IPR020001; KEGG: dhd:Dhaf_4959 60 kDa inner membrane insertion protein; PFAM: Membrane insertion protein, OxaA/YidC; SPTR: Putative uncharacterized protein; TIGRFAM: Membrane insertion protein, OxaA/YidC, core; PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain. | HAMAP: Ribosomal protein L33; InterPro IPR001705; KEGG: dhd:Dhaf_0403 50S ribosomal protein L33; PFAM: Ribosomal protein L33; SPTR: 50S ribosomal protein L33; TIGRFAM: Ribosomal protein L33; PFAM: Ribosomal protein L33; TIGRFAM: ribosomal protein L33, bacterial type; Belongs to the bacterial ribosomal protein bL33 family. | 0.623 |
Sgly_3367 | secA | Sgly_3367 | Sgly_3257 | Membrane protein insertase, YidC/Oxa1 family; COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708: IPR020001; KEGG: dhd:Dhaf_4959 60 kDa inner membrane insertion protein; PFAM: Membrane insertion protein, OxaA/YidC; SPTR: Putative uncharacterized protein; TIGRFAM: Membrane insertion protein, OxaA/YidC, core; PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain. | Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.959 |
Sgly_3367 | secE | Sgly_3367 | Sgly_0378 | Membrane protein insertase, YidC/Oxa1 family; COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708: IPR020001; KEGG: dhd:Dhaf_4959 60 kDa inner membrane insertion protein; PFAM: Membrane insertion protein, OxaA/YidC; SPTR: Putative uncharacterized protein; TIGRFAM: Membrane insertion protein, OxaA/YidC, core; PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain. | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.976 |
Sgly_3367 | secY | Sgly_3367 | Sgly_0411 | Membrane protein insertase, YidC/Oxa1 family; COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708: IPR020001; KEGG: dhd:Dhaf_4959 60 kDa inner membrane insertion protein; PFAM: Membrane insertion protein, OxaA/YidC; SPTR: Putative uncharacterized protein; TIGRFAM: Membrane insertion protein, OxaA/YidC, core; PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain. | Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.982 |
ffh | Sgly_3210 | Sgly_2306 | Sgly_3210 | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.976 |