STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dacAConserved hypothetical protein CHP00159; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (275 aa)    
Predicted Functional Partners:
Sgly_0484
YbbR family protein; COGs: COG4856 conserved hypothetical protein; InterPro IPR012505; KEGG: dsy:DSY4488 hypothetical protein; PFAM: YbbR-like; SPTR: Putative uncharacterized protein; PFAM: YbbR-like protein.
 
  
 0.980
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
   
 
 0.891
Sgly_0866
COGs: COG1109 Phosphomannomutase; InterPro IPR005844: IPR005845: IPR005846: IPR005843; KEGG: pth:PTH_0398 phosphomannomutase; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, C-terminal; SPTR: Phosphomannomutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomanno [...]
   
 
 0.745
Sgly_0485
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG2509 Uncharacterized FAD-dependent dehydrogenase; InterPro IPR013027: IPR006076; KEGG: dhd:Dhaf_0834 FAD dependent oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; SPTR: Putative uncharacterized protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
       0.722
mutS2
DNA mismatch repair protein, MutS family; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
 
     0.636
argR
Transcriptional regulator, ArgR family; Regulates arginine biosynthesis genes.
   
    0.602
Sgly_2218
Alpha-phosphoglucomutase; COGs: COG1109 Phosphomannomutase; InterPro IPR005844: IPR005845; KEGG: dhd:Dhaf_2815 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; SPTR: Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomanno [...]
   
 
 0.601
Sgly_0482
InterPro IPR004518; KEGG: dhd:Dhaf_0830 MazG nucleotide pyrophosphohydrolase; PFAM: NTP pyrophosphohydrolase MazG, putative catalytic core; SPTR: Putative uncharacterized protein; PFAM: MazG nucleotide pyrophosphohydrolase domain.
       0.530
Sgly_1856
CBS domain containing protein; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR001667: IPR003156: IPR000644: IPR002646; KEGG: dhd:Dhaf_3428 polynucleotide adenylyltransferase region; PFAM: Cystathionine beta-synthase, core; Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; Poly A polymerase, head domain; SMART: Cystathionine beta-synthase, core; SPTR: Polynucleotide adenylyltransferase region; PFAM: DHH family; CBS domain; Poly A polymerase head domain.
     
 0.433
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
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