STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sgly_0497NLP/P60 protein; COGs: COG0791 Cell wall-associated hydrolase (invasion-associated protein); InterPro IPR002477: IPR000064; KEGG: dhd:Dhaf_2683 NLP/P60 protein; PFAM: NLP/P60; Peptidoglycan binding-like; SPTR: Putative uncharacterized protein; PFAM: NlpC/P60 family; Putative peptidoglycan binding domain. (222 aa)    
Predicted Functional Partners:
Sgly_0140
COGs: COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains); InterPro IPR008258; KEGG: cbb:CLD_1248 Slt family transglycosylase; PFAM: Lytic transglycosylase-like, catalytic; SPTR: Transglycosylase, SLT family; PFAM: Transglycosylase SLT domain.
 
  
 0.934
Sgly_3222
COGs: COG3409 Putative peptidoglycan-binding domain-containing protein; InterPro IPR002477; KEGG: dsy:DSY1780 hypothetical protein; PFAM: Peptidoglycan binding-like; SPTR: Putative uncharacterized protein; PFAM: Putative peptidoglycan binding domain.
   
0.885
Sgly_0498
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: toc:Toce_1455 two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; SPTR: Putative uncharacterized protein; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
       0.485
Sgly_0499
COGs: COG5002 Signal transduction histidine kinase; InterPro IPR003660: IPR003661: IPR003594; KEGG: toc:Toce_1454 multi-sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SPTR: Multi-sensor signal transduction histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; H [...]
       0.485
Sgly_1221
Fibronectin type III domain protein; COGs: COG5263 FOG: Glucan-binding domain (YG repeat); InterPro IPR003961: IPR013378: IPR001119: IPR002479; KEGG: dhd:Dhaf_2434 cell wall/surface repeat protein; PFAM: Fibronectin, type III; Listeria/Bacterioides repeat; S-layer homology domain; Putative cell wall binding repeat; SPTR: Fibronectin type III domain protein; PFAM: Listeria-Bacteroides repeat domain (List_Bact_rpt); S-layer homology domain; Fibronectin type III domain.
  
    0.436
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.