STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sgly_0641Septum formation initiator; InterPro IPR007060; KEGG: dhd:Dhaf_4070 septum formation initiator; PFAM: Septum formation initiator; SPTR: Septum formation initiator; PFAM: Septum formation initiator; TIGRFAM: cell division protein FtsL. (174 aa)    
Predicted Functional Partners:
Sgly_0651
Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein.
   
 
 0.836
rsmH
Ribosomal RNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
  
  
 0.738
Sgly_0642
COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005543: IPR005311: IPR001460: IPR011927; KEGG: dhd:Dhaf_4069 stage V sporulation protein D; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PASTA; PRIAM: Peptidoglycan glycosyltransferase; SMART: PASTA; SPTR: Stage V sporulation protein D; TIGRFAM: Stage V sporulation protein D; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; PASTA domain; TIGRFAM: stage V sporulation protein D.
  
 
 0.722
mraZ
Protein mraZ; COGs: COG2001 conserved hypothetical protein; HAMAP: MraZ; InterPro IPR020603: IPR003444; KEGG: dsy:DSY2916 cell division protein MraZ; PFAM: MraZ domain; SPTR: Protein mraZ; TIGRFAM: MraZ; PFAM: MraZ protein; TIGRFAM: mraZ protein; Belongs to the MraZ family.
  
  
 0.705
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
     
 0.532
murE
UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
  
    0.482
mraY
Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
       0.464
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
       0.458
Sgly_0647
Cell division-specific peptidoglycan biosynthesis regulator FtsW; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182: IPR013437; KEGG: dsy:DSY2908 hypothetical protein; PFAM: Cell cycle protein; SPTR: Putative uncharacterized protein; TIGRFAM: Cell division protein FtsW; PFAM: Cell cycle protein; TIGRFAM: rod shape-determining protein RodA; stage V sporulation protein E; cell division protein FtsW; Belongs to the SEDS family.
   
 
 0.449
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.