STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurrence
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Experiments
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[Homology]
Score
Sgly_0651Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. (239 aa)    
Predicted Functional Partners:
Sgly_0189
Cyanophycin synthetase; COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; InterPro IPR003135: IPR013651: IPR013221: IPR004101: IPR 011810; KEGG: dsy:DSY0146 cyanophycin synthetase; PFAM: Mur ligase, central; ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type; ATP-grasp fold, RimK-type; Mur ligase, C-terminal; PRIAM: Cyanophycin synthase (L-aspartate-adding); SPTR: Putative uncharacterized protein; TIGRFAM: Cyanophycin synthetase; PFAM: Mur ligase family, glutamate ligase domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Mur ligase middle domain; TIGRFAM: [...]
  
  
 0.965
Sgly_2072
Cell division protein FtsA; COGs: COG0849 Actin-like ATPase involved in cell division; InterPro IPR003494; KEGG: dhd:Dhaf_2994 cell division protein; PFAM: Cell division protein FtsA domain; SPTR: Cell division protein; PFAM: Cell division protein FtsA; TIGRFAM: cell division protein FtsA.
  
 
 0.948
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
  
  
 0.933
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
  
  
 0.896
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
  
 0.879
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
  
 0.875
Sgly_0647
Cell division-specific peptidoglycan biosynthesis regulator FtsW; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182: IPR013437; KEGG: dsy:DSY2908 hypothetical protein; PFAM: Cell cycle protein; SPTR: Putative uncharacterized protein; TIGRFAM: Cell division protein FtsW; PFAM: Cell cycle protein; TIGRFAM: rod shape-determining protein RodA; stage V sporulation protein E; cell division protein FtsW; Belongs to the SEDS family.
 
 
 0.859
Sgly_0642
COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005543: IPR005311: IPR001460: IPR011927; KEGG: dhd:Dhaf_4069 stage V sporulation protein D; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PASTA; PRIAM: Peptidoglycan glycosyltransferase; SMART: PASTA; SPTR: Stage V sporulation protein D; TIGRFAM: Stage V sporulation protein D; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; PASTA domain; TIGRFAM: stage V sporulation protein D.
 
 
 0.852
murB
UDP-N-acetylmuramate dehydrogenase; Cell wall formation.
  
  
 0.852
Sgly_2469
Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311: IPR001460: IPR017790; KEGG: dhd:Dhaf_4348 penicillin-binding protein 2; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Putative uncharacterized protein; TIGRFAM: Penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2.
 
 
 0.850
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
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