STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Sgly_0825KEGG: dhd:Dhaf_2122 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein. (427 aa)    
Predicted Functional Partners:
Sgly_2914
NAD(P)-dependent iron-only hydrogenase catalytic subunit; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterPro IPR001041: IPR019574: IPR004108: IPR003149: IPR 013352; KEGG: cce:Ccel_2467 hydrogenase, Fe-only; PFAM: Iron hydrogenase, large subunit, C-terminal; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; Iron hydrogenase, small subunit-like; SPTR: Hydrogenase, Fe-only; TIGRFAM: Iron hydrogenase, subset; PFAM: Iron only hydrogenase large subunit, C-terminal domain; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Iron h [...]
   
 
 0.868
Sgly_0165
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880: IPR019752: IPR019456: IPR011766: IPR 011895; KEGG: dhd:Dhaf_0054 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (NADP(+)); SPTR: Pyruvate-flavodoxin oxidoreductase; TIGRFAM: Pyruvate-flavo [...]
  
  
 0.804
Sgly_1185
COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: cbe:Cbei_3526 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: Nitroreductase-like; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; PFAM: Nitroreductase family.
 
 
 
 0.773
Sgly_1135
COGs: COG2086 Electron transfer flavoprotein beta subunit; InterPro IPR014730; KEGG: clj:CLJU_c39410 electron transfer flavoprotein subunit beta; PFAM: Electron transfer flavoprotein, alpha/beta-subunit, N-terminal; SPTR: Electron transfer flavoprotein beta-subunit; PFAM: Electron transfer flavoprotein domain.
   
 
 0.719
Sgly_2687
COGs: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; InterPro IPR002023; KEGG: chy:CHY_0731 Fe-hydrogenase, gamma subunit; PFAM: NADH:ubiquinone oxidoreductase, 24kDa subunit; PRIAM: NADH dehydrogenase (quinone); SPTR: Fe-hydrogenase, gamma subunit; PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit.
   
 
 0.650
Sgly_2916
NADH dehydrogenase (quinone); COGs: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; InterPro IPR002023; KEGG: sat:SYN_02139 NADH-quinone oxidoreductase chain F; PFAM: NADH:ubiquinone oxidoreductase, 24kDa subunit; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH dehydrogenase (Ubiquinone) 24 kDa subunit; PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit.
   
 
 0.650
Sgly_2685
NAD-dependent formate dehydrogenase catalytic subunit; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterPro IPR001041: IPR019574: IPR006963: IPR006656: IPR 006657: IPR006478; KEGG: dhd:Dhaf_1398 formate dehydrogenase, alpha subunit; PFAM: Molybdopterin oxidoreductase; Molybdopterin oxidoreductase, Fe4S4 domain; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; Molydopterin dinucleotide-binding domain; PRIAM: Nitrate reductase; SPTR: Formate dehydrogenase, alpha subunit; TIGRFAM: Formate dehydrogenase, alpha subunit; PFAM: Molybdopterin oxidoreducta [...]
   
 
 0.591
Sgly_0375
COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089; KEGG: ckr:CKR_1969 hypothetical protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Putative uncharacterized protein; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Methyl-accepting chemotaxis protein (MCP) signaling domain.
   
  
0.547
Sgly_2185
Hydrogenase, Fe-only; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterPro IPR006311: IPR013352: IPR004108: IPR003149; KEGG: dhd:Dhaf_4621 hydrogenase, Fe-only; PFAM: Iron hydrogenase, large subunit, C-terminal; Iron hydrogenase, small subunit-like; PRIAM: Ferredoxin hydrogenase; SPTR: Hydrogenase, Fe-only; TIGRFAM: Iron hydrogenase, subset; Twin-arginine translocation pathway, signal sequence; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Iron hydrogenase small subunit; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence; hydroge [...]
   
   0.535
Sgly_2188
Hydrogenase, Fe-only; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterPro IPR006311: IPR013352: IPR004108: IPR003149; KEGG: dsy:DSY4712 putative hydrogenase large subunit; PFAM: Iron hydrogenase, large subunit, C-terminal; Iron hydrogenase, small subunit-like; PRIAM: Ferredoxin hydrogenase; SPTR: Putative hydrogenase large subunit; TIGRFAM: Iron hydrogenase, subset; Twin-arginine translocation pathway, signal sequence; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Iron hydrogenase small subunit; TIGRFAM: hydrogenases, Fe-only.
   
   0.535
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
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