STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sgly_0982Peptidase S1 and S6 chymotrypsin/Hap; COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001478: IPR001254; KEGG: ttm:Tthe_0681 peptidase S1 and S6 chymotrypsin/Hap; PFAM: Peptidase S1/S6, chymotrypsin/Hap; SMART: PDZ/DHR/GLGF; SPTR: Putative uncharacterized protein; PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF). (384 aa)    
Predicted Functional Partners:
Sgly_3320
Peptidase S1 and S6 chymotrypsin/Hap; COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001254: IPR001478; KEGG: dhd:Dhaf_4915 2-alkenal reductase; PFAM: Peptidase S1/S6, chymotrypsin/Hap; PDZ/DHR/GLGF; SMART: PDZ/DHR/GLGF; SPTR: Putative uncharacterized protein; PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF).
  
  
 
0.916
Sgly_2570
AAA ATPase central domain protein; COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003593: IPR003959; KEGG: dsy:DSY3406 hypothetical protein; PFAM: ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core; SPTR: Putative uncharacterized protein; PFAM: ATPase family associated with various cellular activities (AAA).
   
 0.774
Sgly_0983
Protein of unknown function DUF214; COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: ccb:Clocel_3453 hypothetical protein; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: Putative uncharacterized protein; PFAM: Predicted permease.
   
   0.615
Sgly_0984
Phosphonate-transporting ATPase; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593: IPR003439; KEGG: ccb:Clocel_3452 ABC transporter related; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; PFAM: ABC transporter.
       0.603
Sgly_0985
COGs: COG0845 Membrane-fusion protein; KEGG: gct:GC56T3_2852 biotin/lipoyl attachment domain-containing protein; SPTR: Biotin/lipoyl attachment domain-containing protein.
     
 0.600
Sgly_0986
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661: IPR003594; KEGG: ccb:Clocel_3449 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
  
 0.564
Sgly_1406
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
   
 0.513
Sgly_0987
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: ccb:Clocel_3448 two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcripti [...]
  
    0.507
rplT
LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
  
   0.498
rplK
LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
    
   0.497
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.