STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Sgly_1018COGs: COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit BcrC/BadD/HgdB; InterPro IPR010327; KEGG: gur:Gura_3877 2-hydroxyglutaryl-CoA dehydratase, D-component; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; SPTR: 2-hydroxyglutaryl-CoA dehydratase, D-component; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component. (390 aa)    
Predicted Functional Partners:
Sgly_1017
CoA-substrate-specific enzyme activase; COGs: COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); InterPro IPR008275: IPR002731; KEGG: mpl:Mpal_1148 CoA-substrate-specific enzyme activase; PFAM: ATPase, BadF/BadG/BcrA/BcrD type; PRIAM: Benzoyl-CoA reductase; SPTR: CoA-substrate-specific enzyme activase; TIGRFAM: CoA enzyme activase; PFAM: BadF/BadG/BcrA/BcrD ATPase family; TIGRFAM: CoA-substrate-specific enzyme activase, putative; benzoyl-CoA reductase, bzd-type, Q subunit; benzoyl-CoA reductase, bcr type, subunit D.
 
 0.998
Sgly_1019
COGs: COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit BcrC/BadD/HgdB; InterPro IPR010327; KEGG: mpl:Mpal_1137 2-hydroxyglutaryl-CoA dehydratase D-component; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; SPTR: 2-hydroxyglutaryl-CoA dehydratase D-component; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component.
 
    
0.833
Sgly_1020
Extracellular solute-binding protein family 3; COGs: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components; InterPro IPR001638; KEGG: gym:GYMC10_5033 NMT1/THI5 like domain protein; SMART: Extracellular solute-binding protein, family 3; SPTR: NMT1/THI5 like domain protein; PFAM: NMT1/THI5 like.
       0.695
Sgly_0439
CoA-substrate-specific enzyme activase; COGs: COG3580 conserved hypothetical protein; InterPro IPR002731: IPR018709: IPR008275; KEGG: swo:Swol_1945 putative activator of (R) -2-hydroxyglutaryl-CoA dehydratase; PFAM: Protein of unknown function DUF2229, CoA enzyme activase; ATPase, BadF/BadG/BcrA/BcrD type; SPTR: Putative activator of (R)-2-hydroxyglutaryl-coA dehydratase; TIGRFAM: CoA enzyme activase; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; BadF/BadG/BcrA/BcrD ATPase family; CoA enzyme activase uncharacterised domain (DUF2229); TIGRFAM: CoA-substrate-specific enzyme activ [...]
  
 
 0.631
Sgly_3319
CoA-substrate-specific enzyme activase; COGs: COG3580 conserved hypothetical protein; InterPro IPR002731: IPR018709: IPR008275; KEGG: cth:Cthe_1329 putative CoA-substrate-specific enzyme activase; PFAM: Protein of unknown function DUF2229, CoA enzyme activase; ATPase, BadF/BadG/BcrA/BcrD type; SPTR: CoA-substrate-specific enzyme activase; TIGRFAM: CoA enzyme activase; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; BadF/BadG/BcrA/BcrD ATPase family; CoA enzyme activase uncharacterised domain (DUF2229); TIGRFAM: CoA-substrate-specific enzyme activase, putative.
  
 
 0.631
Sgly_1015
Taurine-transporting ATPase; COGs: COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system ATPase component; InterPro IPR003593: IPR003439; KEGG: mja:MJ_0412 nitrate transporter protein NrtC homolog CmpC; PFAM: ABC transporter-like; PRIAM: Taurine-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Uncharacterized ABC transporter ATP-binding protein MJ0412; PFAM: ABC transporter.
       0.594
Sgly_1016
Binding-protein-dependent transport systems inner membrane component; COGs: COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system permease component; InterPro IPR000515; KEGG: tjr:TherJR_2469 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.
       0.594
Sgly_2352
COGs: COG1456 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein); KEGG: geo:Geob_2483 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein)-like protein; SPTR: CO dehydrogenase/acetyl-CoA synthase gamma subunit (Corrinoid Fe-S protein)-like protein; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit.
  
     0.483
Sgly_2537
COGs: COG0407 Uroporphyrinogen-III decarboxylase; InterPro IPR000257; KEGG: cth:Cthe_2786 methylcobalamin:coenzyme M methyltransferase; PFAM: Uroporphyrinogen decarboxylase (URO-D); SPTR: Methyltransferase MtaA/CmuA family; PFAM: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase, MtaA/CmuA family.
  
    0.445
Sgly_1021
InterPro IPR011701; KEGG: dae:Dtox_1613 major facilitator superfamily MFS_1; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1; PFAM: Bacterial protein of unknown function (DUF894).
       0.430
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
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