STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Sgly_1181COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660: IPR004089; KEGG: cbt:CLH_2362 methyl-accepting chemotaxis sensory transducer; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Methyl-accepting chemotaxis sensory transducer; PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain. (596 aa)    
Predicted Functional Partners:
Sgly_1174
CheA signal transduction histidine kinase; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterPro IPR008207: IPR003594: IPR002545: IPR004105; KEGG: cce:Ccel_2315 CheA signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup, homodimeric; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; CheW-like protein; SMART: CheW-like protein; ATPase-like, ATP-binding domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; SPTR: CheA signal transduction histidine kinase; [...]
 
 0.995
Sgly_1175
CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: dae:Dtox_0612 CheW protein; PFAM: CheW-like protein; SMART: CheW-like protein; SPTR: CheW protein; PFAM: CheW-like domain.
 
 0.995
Sgly_0590
CheA signal transduction histidine kinase; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterPro IPR008207: IPR010808: IPR004105: IPR003594: IPR 002545; KEGG: dhd:Dhaf_4155 CheA signal transduction histidine kinase; PFAM: CheW-like protein; ATPase-like, ATP-binding domain; Signal transduction histidine kinase, P2 response regulator-binding; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; Signal transduction histidine kinase, subgroup, homodimeric; SMART: CheW-like protein; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; A [...]
 
 0.992
Sgly_0591
CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: dhd:Dhaf_4154 CheW protein; PFAM: CheW-like protein; SMART: CheW-like protein; SPTR: Putative uncharacterized protein; PFAM: CheW-like domain.
 
 0.991
Sgly_1176
MCP methyltransferase, CheR-type; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR000780; KEGG: cth:Cthe_0808 MCP methyltransferase, CheR-type; PFAM: MCP methyltransferase, CheR-type; PRIAM: Protein-glutamate O-methyltransferase; SMART: MCP methyltransferase, CheR-type; SPTR: MCP methyltransferase, CheR-type; PFAM: CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain.
 
 0.991
Sgly_1177
CheB methylesterase; COGs: COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain; InterPro IPR000673; KEGG: cce:Ccel_2310 CheB methylesterase; PFAM: Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase; PRIAM: Protein-glutamate methylesterase; SPTR: Response regulator receiver modulated CheB methylesterase; PFAM: CheB methylesterase.
 0.991
Sgly_1649
Response regulator receiver modulated CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545: IPR001789; KEGG: cno:NT01CX_2338 chemotaxis protein CheV-like protein; PFAM: Signal transduction response regulator, receiver domain; CheW-like protein; SMART: Signal transduction response regulator, receiver domain; CheW-like protein; SPTR: Putative chemotaxis protein CheV; PFAM: CheW-like domain; Response regulator receiver domain.
 
 0.990
Sgly_1178
CheD; COGs: COG1871 Chemotaxis protein; stimulates methylation of MCP protein; KEGG: pca:Pcar_1201 CheD-like chemotaxis protein; SPTR: Probable chemoreceptor glutamine deamidase CheD; PFAM: CheD.
 
  0.986
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 0.983
Sgly_2652
MCP methyltransferase, CheR-type; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR000780; KEGG: dhd:Dhaf_4203 MCP methyltransferase, CheR-type; PFAM: MCP methyltransferase, CheR-type; PRIAM: Protein-glutamate O-methyltransferase; SMART: MCP methyltransferase, CheR-type; SPTR: MCP methyltransferase, CheR-type; PFAM: CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain.
 0.979
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
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