STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sgly_1315Putative transcriptional regulator, GntR family; COGs: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR004839; KEGG: ckr:CKR_0384 hypothetical protein; PFAM: Aminotransferase, class I/II; PRIAM: Aromatic-amino-acid transaminase; SPTR: Putative uncharacterized protein; PFAM: Aminotransferase class I and II. (395 aa)    
Predicted Functional Partners:
Sgly_1900
Fumarate reductase/succinate dehydrogenase flavoprotein domain protein; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR003953; KEGG: chy:CHY_0930 heterodisulfide reductase, subunit A, selenocysteine-containing; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; SPTR: Heterodisulfide reductase, subunit A, selenocysteine-containing; PFAM: FAD binding domain.
    
   0.553
Sgly_2398
NGG1p interacting factor 3 protein, NIF3; COGs: COG3323 conserved hypothetical protein; InterPro IPR002678; KEGG: dhd:Dhaf_4214 protein of unknown function DUF34; PFAM: NGG1p interacting factor 3, NIF3; SPTR: Putative uncharacterized protein; TIGRFAM: NGG1p interacting factor 3, NIF3; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: dinuclear metal center protein, YbgI/SA1388 family; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
   
    0.497
Sgly_1316
KEGG: dsy:DSY0734 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated.
       0.462
Sgly_1379
Dihydroorotate oxidase B, catalytic subunit; COGs: COG0167 Dihydroorotate dehydrogenase; InterPro IPR012135: IPR005720; KEGG: cbe:Cbei_1943 dihydropyrimidine dehydrogenase; PFAM: Dihydroorotate dehydrogenase, class 1/ 2; PRIAM: Dihydropyrimidine dehydrogenase (NADP(+)); SPTR: Dihydroorotate dehydrogenase family protein; TIGRFAM: Dihydroorotate dehydrogenase, class 1, core; PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase (subfamily 1) family protein.
   
 
 0.411
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.