STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Sgly_1425Sodium/proton antiporter, CPA1 family; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (677 aa)    
Predicted Functional Partners:
Sgly_0491
Cl- channel voltage-gated family protein; COGs: COG0038 Chloride channel protein EriC; InterPro IPR001807: IPR006037; KEGG: drm:Dred_2944 Cl-channel, voltage-gated family protein; PFAM: Chloride channel, voltage gated; Regulator of K+ conductance, C-terminal; SPTR: Cl-channel, voltage-gated family protein; PFAM: Voltage gated chloride channel; TrkA-C domain.
  
  
 0.602
Sgly_1424
modD protein; COGs: COG0157 Nicotinate-nucleotide pyrophosphorylase; InterPro IPR002638: IPR006242; KEGG: clj:CLJU_c38070 nicotinate-nucleotide diphosphorylase; PFAM: Quinolinate phosphoribosyl transferase; PRIAM: Nicotinate-nucleotide diphosphorylase (carboxylating); SPTR: ModD protein; TIGRFAM: Putative molybdenum utilization protein ModD; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; putative molybdenum utilization protein ModD; Belongs to the NadC/ModD family.
       0.506
Sgly_2813
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.457
Sgly_0688
ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG0474 Cation transport ATPase; InterPro IPR004014: IPR008250: IPR005834: IPR006068: IPR 001757; KEGG: dsy:DSY2749 hypothetical protein; PFAM: ATPase, P-type, ATPase-associated domain; ATPase, P-type cation-transporter, N-terminal; Haloacid dehalogenase-like hydrolase; ATPase, P-type cation-transporter, C-terminal; PRIAM: Calcium-transporting ATPase; SPTR: Putative uncharacterized protein; TIGRFAM: ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; Cation [...]
    
 
 0.406
Sgly_1625
Calcium-translocating P-type ATPase, PMCA-type; COGs: COG0474 Cation transport ATPase; InterPro IPR006408: IPR001757: IPR004014: IPR008250: IPR 005834: IPR006068; KEGG: csc:Csac_0369 calcium-translocating P-type ATPase, PMCA-type; PFAM: ATPase, P-type, ATPase-associated domain; ATPase, P-type cation-transporter, N-terminal; Haloacid dehalogenase-like hydrolase; ATPase, P-type cation-transporter, C-terminal; PRIAM: Calcium-transporting ATPase; SPTR: Calcium-translocating P-type ATPase, PMCA-type; TIGRFAM: ATPase, P-type, calcium-transporting, PMCA-type; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/ [...]
    
 
 0.406
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
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