STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sgly_1586InterPro IPR000326; KEGG: tit:Thit_2198 phosphoesterase PA-phosphatase related protein; PFAM: Phosphatidic acid phosphatase type 2/haloperoxidase; SMART: Phosphatidic acid phosphatase type 2/haloperoxidase; SPTR: Phosphoesterase PA-phosphatase related protein; PFAM: PAP2 superfamily. (172 aa)    
Predicted Functional Partners:
mraY
Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
  
 0.929
uppP
Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
  
 
 0.928
Sgly_2423
COGs: COG0818 Diacylglycerol kinase; InterPro IPR000829; KEGG: lsg:lse_1381 hypothetical protein; PFAM: Diacylglycerol kinase, prokaryotic; SPTR: DgkA protein; PFAM: Prokaryotic diacylglycerol kinase.
    
 0.923
Sgly_0460
Di-trans,poly-cis-decaprenylcistransferase; COGs: COG0020 Undecaprenyl pyrophosphate synthase; InterPro IPR001441; KEGG: clj:CLJU_c35470 undecaprenyl pyrophosphate synthase; PFAM:Di-trans-poly-cis-decaprenylcistransferase-lik e; PRIAM: Di-trans,poly-cis-decaprenylcistransferase; SPTR: Undecaprenyl pyrophosphate synthase; PFAM: Putative undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase.
  
 
 0.914
Sgly_2263
Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
  
 
 0.914
Sgly_1129
o-succinylbenzoate--CoA ligase; COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: rca:Rcas_1775 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: o-succinylbenzoate--CoA ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme.
    
 0.906
rplF
LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.696
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
   0.666
msrA
Peptide methionine sulfoxide reductase msrB; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 
 0.525
Sgly_1587
Lysine exporter protein (LYSE/YGGA); COGs: COG1280 Putative threonine efflux protein; InterPro IPR001123; KEGG: ppd:Ppro_1992 lysine exporter protein LysE/YggA; PFAM: Lysine exporter protein (LYSE/YGGA); SPTR: Lysine exporter protein (LYSE/YGGA); PFAM: LysE type translocator.
       0.498
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.