STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sgly_1725COGs: COG0681 Signal peptidase I; InterPro IPR000223: IPR019759; KEGG: dhd:Dhaf_3289 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; PRIAM: Signal peptidase I; SPTR: Putative uncharacterized protein; TIGRFAM: Peptidase S26A, signal peptidase I; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family. (186 aa)    
Predicted Functional Partners:
Sgly_0454
Signal peptidase I; InterPro IPR019759: IPR000223; KEGG: cth:Cthe_2079 thylakoidal processing peptidase; PFAM: Peptidase S24/S26A/S26B, conserved region; SPTR: Thylakoidal processing peptidase. Serine peptidase. MEROPS family S26A; TIGRFAM: Peptidase S26A, signal peptidase I; PFAM: Peptidase S26; Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type.
  
  
 
0.925
Sgly_1761
Signal peptidase I; InterPro IPR000223: IPR019759; KEGG: dhd:Dhaf_2722 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; SPTR: Signal peptidase I; TIGRFAM: Peptidase S26A, signal peptidase I; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family.
  
  
 
0.922
Sgly_1726
Protein of unknown function DUF815; COGs: COG2607 ATPase (AAA+ superfamily); InterPro IPR008533; KEGG: dhd:Dhaf_3284 protein of unknown function DUF815; PFAM: Protein of unknown function DUF815; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF815).
       0.746
Sgly_2259
Membrane-associated zinc metalloprotease; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR008915: IPR001478: IPR004387; KEGG: dsy:DSY2538 hypothetical protein; PFAM: Peptidase M50; PDZ/DHR/GLGF; SMART: PDZ/DHR/GLGF; SPTR: Putative uncharacterized protein; TIGRFAM: Peptidase M50, putative membrane-associated zinc metallopeptidase; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP.
 
  
 0.597
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
 
 
 0.596
Sgly_2702
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterPro IPR000583: IPR006982: IPR002932: IPR002489; KEGG: dae:Dtox_3758 glutamate synthase (ferredoxin); PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
     
 0.556
minE
Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
  
    0.521
Sgly_1724
Cupin 2 conserved barrel domain protein; COGs: COG1917 conserved hypothetical protein contains double-stranded beta-helix domain; InterPro IPR013096; KEGG: hmo:HM1_2283 hypothetical protein; PFAM: Cupin 2, conserved barrel; SPTR: Putative uncharacterized protein; PFAM: Cupin domain.
  
    0.516
rnhB
RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
    0.462
murJ
Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
  
     0.454
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.